Oliver Braubach

TL;DR: A detailed catalog of zebrafish behaviors that covers both larval and adult models is developed, representing a beginning of creating a more comprehensive ethogram ofZebrafish behavior, which will improve interpretation of published findings, foster cross-species behavioral modeling, and encourage new groups to apply zebra fish neurobehavioral paradigms in their research.

TL;DR: The Zebrafish is emerging as a new important species for studying mechanisms of brain function and dysfunction and the potential of zebrafish models in behavioral phenomics and high-throughput genetic/small molecule screening, which is critical for CNS drug discovery and identifying novel candidate genes.

TL;DR: This study demonstrates trans-BBB delivery of tumor-targeted polymer-conjugated checkpoint inhibitors as an effective GBM treatment via activation of both systemic and local privileged brain tumor immune response.

TL;DR: Zebrafish olfactory behaviors and their modification through learning are characterized, using an apparatus consisting of a circular flow-through tank that allows controlled administration of odorants, for the first demonstration of a classically conditioned appetitive response to a behaviorally neutral odorant in fish.

TL;DR: The results provide a uniquely detailed description of a vertebrate olfactory system and highlight anatomically distinct parallel neural pathways that mediate early aspects of olfaction processing in the zebrafish.