Robin Antrobus

TL;DR: This study proposes that there are at least two populations of intracellular CCVs: one containing both GGAs and AP-1 for anterograde trafficking and another containing AP- 1 for retrograde trafficking, and shows that knocksideways and proteomics are a powerful combination for investigating protein function.

TL;DR: The UL138-mediated loss of MRP1 provides a marker for detecting latent HCMV infection and a therapeutic target for eliminating latently infected cells before transplantation.

TL;DR: Nuclear localization of SQSTM1 and its association with DDF increase with aging and are prevented by life-span-extending dietary restriction, suggesting that an imbalance in the mechanism identified here may contribute to aging and age-related diseases.

TL;DR: A structure-based bioinformatics tool was developed, and the core subunits of TSET, a 'missing link' between the APs and COPI, were identified, which provides new insights into early eukaryotic evolution.

TL;DR: The finding that melanoma TEV downregulated type I interferon receptor and expression of IFN-inducible cholesterol 25-hydroxylase (CH25H) suggests the importance of CH25H in defense against education of normal cells by TEV and argues for the use of reserpine in adjuvant melanoma therapy.