R
Roger Tavendale
Researcher at University of Dundee
Publications - 73
Citations - 5554
Roger Tavendale is an academic researcher from University of Dundee. The author has contributed to research in topics: Asthma & Population. The author has an hindex of 33, co-authored 71 publications receiving 5085 citations. Previous affiliations of Roger Tavendale include Texas Biomedical Research Institute & Ninewells Hospital.
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Journal ArticleDOI
An Obesity-Associated FTO Gene Variant and Increased Energy Intake in Children
TL;DR: The FTO variant that confers a predisposition to obesity does not appear to be involved in the regulation of energy expenditure but may have a role in the control of food intake and food choice, suggesting a link to a hyperphagic phenotype or a preference for energy-dense foods.
Journal ArticleDOI
Common variants in WFS1 confer risk of type 2 diabetes
Manjinder S. Sandhu,Manjinder S. Sandhu,Michael N. Weedon,Katherine A. Fawcett,Jon Wasson,Sally L Debenham,Allan Daly,Hana Lango,Timothy M. Frayling,Rosalind J Neumann,Richard Sherva,Ilana Blech,Paul D.P. Pharoah,Paul D.P. Pharoah,Colin N. A. Palmer,Charlotte H. Kimber,Roger Tavendale,Andrew D. Morris,Mark I. McCarthy,Mark I. McCarthy,Mark Walker,Graham A. Hitman,Benjamin Glaser,M. Alan Permutt,Andrew T. Hattersley,Nicholas J. Wareham,Inês Barroso +26 more
TL;DR: Using a gene-centric approach, it is shown that variation in WFS1 also predisposes to common type 2 diabetes.
Journal ArticleDOI
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.
Kaixin Zhou,Kaixin Zhou,Céline Bellenguez,Chris C. A. Spencer,Amanda J. Bennett,Ruth L. Coleman,Ruth L. Coleman,Roger Tavendale,Roger Tavendale,Simon A. Hawley,Louise A. Donnelly,Louise A. Donnelly,Christopher Schofield,Christopher Schofield,Christopher J. Groves,Christopher J. Groves,Lindsay Burch,Lindsay Burch,Fiona Carr,Fiona Carr,Amy Strange,Colin Freeman,Jenefer M. Blackwell,Elvira Bramon,Elvira Bramon,Matthew A. Brown,Matthew A. Brown,Juan P. Casas,Juan P. Casas,Aiden Corvin,N. Craddock,Panos Deloukas,Panos Deloukas,Serge Dronov,Serge Dronov,A. Duncanson,Sarah Edkins,Sarah Edkins,Emma Gray,Emma Gray,Sarah E. Hunt,Sarah E. Hunt,Joachim Jankowski,Joachim Jankowski,Joachim Jankowski,Cordelia Langford,Cordelia Langford,Hugh S. Markus,Christopher G. Mathew,Robert Plomin,Anna Rautanen,Stephen Sawcer,Nilesh J. Samani,Nilesh J. Samani,Nilesh J. Samani,Richard C. Trembath,Ananth C. Viswanathan,Nicholas W. Wood,Lorna W. Harries,Lorna W. Harries,Andrew T. Hattersley,Andrew T. Hattersley,Alex S. F. Doney,Alex S. F. Doney,Helen M. Colhoun,Andrew D. Morris,Calum Sutherland,Calum Sutherland,D. G. Hardie,D. G. Hardie,Leena Peltonen,Mark I. McCarthy,Rury R. Holman,Colin N. A. Palmer,Colin N. A. Palmer,Peter Donnelly,Ewan R. Pearson +76 more
TL;DR: It is concluded that ATM, a gene known to be involved in DNA repair and cell cycle control, plays a role in the effect of metformin upstream of AMP-activated protein kinase, and variation in this gene alters glycemic response to meetformin.
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
Kaixin Zhou,Kaixin Zhou,Céline Bellenguez,Chris C. A. Spencer,Amanda J. Bennett,Ruth L. Coleman,Ruth L. Coleman,Roger Tavendale,Roger Tavendale,Simon A. Hawley,Louise A. Donnelly,Louise A. Donnelly,Christopher Schofield,Christopher Schofield,Christopher J. Groves,Christopher J. Groves,Lindsay Burch,Lindsay Burch,Fiona Carr,Fiona Carr,Amy Strange,Colin Freeman,Jenefer M. Blackwell,Elvira Bramon,Elvira Bramon,Matthew A. Brown,Matthew A. Brown,Juan P. Casas,Juan P. Casas,Aiden Corvin,N. Craddock,Panos Deloukas,Panos Deloukas,Serge Dronov,Serge Dronov,A. Duncanson,Sarah Edkins,Sarah Edkins,Emma Gray,Emma Gray,Sarah E. Hunt,Sarah E. Hunt,Joachim Jankowski,Joachim Jankowski,Joachim Jankowski,Cordelia Langford,Cordelia Langford,Hugh S. Markus,Christopher G. Mathew,Robert Plomin,Anna Rautanen,Stephen Sawcer,Nilesh J. Samani,Nilesh J. Samani,Nilesh J. Samani,Richard C. Trembath,Ananth C. Viswanathan,Nicholas W. Wood,Lorna W. Harries,Lorna W. Harries,Andrew T. Hattersley,Andrew T. Hattersley,Alex S. F. Doney,Alex S. F. Doney,Helen M. Colhoun,Andrew D. Morris,Calum Sutherland,Calum Sutherland,D. G. Hardie,D. G. Hardie,Leena Peltonen,Mark I. McCarthy,Rury R. Holman,Colin N. A. Palmer,Colin N. A. Palmer,Peter Donnelly,Ewan R. Pearson +76 more
TL;DR: A genome-wide association study for glycemic response to metformin in 1,024 Scottish individuals with type 2 diabetes with replication in two cohorts including 1,783 Scottish individuals and 1,113 individuals from the UK Prospective Diabetes Study.
Journal ArticleDOI
Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish heart health study: cohort study
TL;DR: An anomalous coronary protective role for type A behaviour in women; raised plasma fibrinogen as a strong predictor of all end points; and an unexpectedly powerful protective relation of dietary potassium to all cause mortality are found.