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Amy Strange

Researcher at University of Oxford

Publications -  17
Citations -  6889

Amy Strange is an academic researcher from University of Oxford. The author has contributed to research in topics: Genome-wide association study & Genetic association. The author has an hindex of 13, co-authored 13 publications receiving 6037 citations. Previous affiliations of Amy Strange include Wellcome Trust Centre for Human Genetics.

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Genome-wide association study identifies five new schizophrenia loci

Stephan Ripke, +210 more
- 01 Oct 2011 - 
TL;DR: The authors examined the role of common genetic variation in schizophrenia in a genome-wide association study of substantial size: a stage 1 discovery sample of 21,856 individuals of European ancestry and a stage 2 replication sample of 29,839 independent subjects.
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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Ashley Beecham, +206 more
- 01 Nov 2013 - 
TL;DR: This study enhances the catalog of multiple sclerosis risk variants and illustrates the value of fine mapping in the resolution of GWAS signals.
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A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

Amy Strange, +85 more
- 01 Nov 2010 - 
TL;DR: These findings implicate pathways that integrate epidermal barrier dysfunction with innate and adaptive immune dysregulation in psoriasis pathogenesis and report compelling evidence for an interaction between the HLA-C and ERAP1 loci.
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Lam C. Tsoi, +215 more
- 01 Dec 2012 - 
TL;DR: A meta-analysis of genome-wide association studies and independent data sets genotyped on the Immunochip identified 15 new susceptibility loci, increasing to 36 the number associated with psoriasis in European individuals, and identified five independent signals within previously known loci.
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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Douglas M. Ruderfer, +631 more
- 14 Jun 2018 - 
TL;DR: For the first time, specific loci that distinguish between BD and SCZ are discovered and polygenic components underlying multiple symptom dimensions are identified that point to the utility of genetics to inform symptomology and potential treatment.