K
Kaixin Zhou
Researcher at University of Dundee
Publications - 72
Citations - 4982
Kaixin Zhou is an academic researcher from University of Dundee. The author has contributed to research in topics: Type 2 diabetes & Medicine. The author has an hindex of 32, co-authored 54 publications receiving 4460 citations. Previous affiliations of Kaixin Zhou include King's College London & Texas Biomedical Research Institute.
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Journal ArticleDOI
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes.
Keeley J. Brookes,Xiaohui Xu,Wei J. Chen,Kaixin Zhou,Benjamin M. Neale,N. Lowe,R. Aneey,Barbara Franke,Michael Gill,Richard P. Ebstein,Jan K. Buitelaar,Pak C. Sham,Desmond Campbell,Joanne Knight,Penny Andreou,Marieke E. Altink,Raoul Arnold,Frits Boer,Cathelijne J. M. Buschgens,Louise Butler,Hanna Christiansen,Leonard C. Feldman,K. Fleischman,Ellen A. Fliers,Raoul Howe-Forbes,A. Goldfarb,Alexander Heise,Isabel Gabriëls,Isabelle Korn-Lubetzki,Rafaela Marco,She'era Medad,Rudolf Minderaa,Fernando Mulas,Ueli C Müller,Aisling Mulligan,K. Rabin,Nanda Rommelse,Vaheshta Sethna,J. Sorohan,Henrik Uebel,Lamprini Psychogiou,Anne Weeks,R. Barrett,Ian W. Craig,Tobias Banaschewski,Edmund J.S. Sonuga-Barke,J. Eisenberg,Jonna Kuntsi,Iris Manor,Peter McGuffin,Ana Miranda,Robert D. Oades,Robert Plomin,Herbert Roeyers,Aribert Rothenberger,Joseph A. Sergeant,Hans-Christoph Steinhausen,Eric Taylor,Margaret Thompson,Stephen V. Faraone,Philip Asherson,Lena Johansson +61 more
TL;DR: In this article, the authors examined 1038 single-nucleotide polymorphisms (SNPs) spanning 51 candidate genes involved in the regulation of neurotransmitter pathways, particularly dopamine, norepinephrine and serotonin pathways, in addition to circadian rhythm genes.
Journal ArticleDOI
Genome-wide association scan of quantitative traits for Attention Deficit Hyperactivity Disorder identifies novel associations and confirms candidate gene associations
Jessica Lasky-Su,Benjamin M. Neale,Barbara Franke,Richard Anney,Kaixin Zhou,Julian Maller,Alejandro Arias Vasquez,Wai Chen,Philip Asherson,Jan K. Buitelaar,Tobias Banaschewski,Richard P. Ebstein,Michael Gill,Ana Miranda,Fernando Mulas,Robert D. Oades,Herbert Roeyers,Aribert Rothenberger,Joseph A. Sergeant,Edmund J.S. Sonuga-Barke,Hans-Christoph Steinhausen,Eric Taylor,Mark J. Daly,Mark J. Daly,Nan M. Laird,Christoph Lange,Christoph Lange,Stephen V. Faraone +27 more
TL;DR: Novel genetic associations at viable ADHD candidate genes are identified and confirmatory evidence for associations at previous candidate genes is provided to confirm the proposed genetic variants for ADHD.
Journal ArticleDOI
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.
Kaixin Zhou,Kaixin Zhou,Céline Bellenguez,Chris C. A. Spencer,Amanda J. Bennett,Ruth L. Coleman,Ruth L. Coleman,Roger Tavendale,Roger Tavendale,Simon A. Hawley,Louise A. Donnelly,Louise A. Donnelly,Christopher Schofield,Christopher Schofield,Christopher J. Groves,Christopher J. Groves,Lindsay Burch,Lindsay Burch,Fiona Carr,Fiona Carr,Amy Strange,Colin Freeman,Jenefer M. Blackwell,Elvira Bramon,Elvira Bramon,Matthew A. Brown,Matthew A. Brown,Juan P. Casas,Juan P. Casas,Aiden Corvin,N. Craddock,Panos Deloukas,Panos Deloukas,Serge Dronov,Serge Dronov,A. Duncanson,Sarah Edkins,Sarah Edkins,Emma Gray,Emma Gray,Sarah E. Hunt,Sarah E. Hunt,Joachim Jankowski,Joachim Jankowski,Joachim Jankowski,Cordelia Langford,Cordelia Langford,Hugh S. Markus,Christopher G. Mathew,Robert Plomin,Anna Rautanen,Stephen Sawcer,Nilesh J. Samani,Nilesh J. Samani,Nilesh J. Samani,Richard C. Trembath,Ananth C. Viswanathan,Nicholas W. Wood,Lorna W. Harries,Lorna W. Harries,Andrew T. Hattersley,Andrew T. Hattersley,Alex S. F. Doney,Alex S. F. Doney,Helen M. Colhoun,Andrew D. Morris,Calum Sutherland,Calum Sutherland,D. G. Hardie,D. G. Hardie,Leena Peltonen,Mark I. McCarthy,Rury R. Holman,Colin N. A. Palmer,Colin N. A. Palmer,Peter Donnelly,Ewan R. Pearson +76 more
TL;DR: It is concluded that ATM, a gene known to be involved in DNA repair and cell cycle control, plays a role in the effect of metformin upstream of AMP-activated protein kinase, and variation in this gene alters glycemic response to meetformin.
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
Kaixin Zhou,Kaixin Zhou,Céline Bellenguez,Chris C. A. Spencer,Amanda J. Bennett,Ruth L. Coleman,Ruth L. Coleman,Roger Tavendale,Roger Tavendale,Simon A. Hawley,Louise A. Donnelly,Louise A. Donnelly,Christopher Schofield,Christopher Schofield,Christopher J. Groves,Christopher J. Groves,Lindsay Burch,Lindsay Burch,Fiona Carr,Fiona Carr,Amy Strange,Colin Freeman,Jenefer M. Blackwell,Elvira Bramon,Elvira Bramon,Matthew A. Brown,Matthew A. Brown,Juan P. Casas,Juan P. Casas,Aiden Corvin,N. Craddock,Panos Deloukas,Panos Deloukas,Serge Dronov,Serge Dronov,A. Duncanson,Sarah Edkins,Sarah Edkins,Emma Gray,Emma Gray,Sarah E. Hunt,Sarah E. Hunt,Joachim Jankowski,Joachim Jankowski,Joachim Jankowski,Cordelia Langford,Cordelia Langford,Hugh S. Markus,Christopher G. Mathew,Robert Plomin,Anna Rautanen,Stephen Sawcer,Nilesh J. Samani,Nilesh J. Samani,Nilesh J. Samani,Richard C. Trembath,Ananth C. Viswanathan,Nicholas W. Wood,Lorna W. Harries,Lorna W. Harries,Andrew T. Hattersley,Andrew T. Hattersley,Alex S. F. Doney,Alex S. F. Doney,Helen M. Colhoun,Andrew D. Morris,Calum Sutherland,Calum Sutherland,D. G. Hardie,D. G. Hardie,Leena Peltonen,Mark I. McCarthy,Rury R. Holman,Colin N. A. Palmer,Colin N. A. Palmer,Peter Donnelly,Ewan R. Pearson +76 more
TL;DR: A genome-wide association study for glycemic response to metformin in 1,024 Scottish individuals with type 2 diabetes with replication in two cohorts including 1,783 Scottish individuals and 1,113 individuals from the UK Prospective Diabetes Study.
Journal ArticleDOI
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Momoko Horikoshi,Hanieh Yaghootkar,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Ulla Sovio,Ulla Sovio,H. Rob Taal,Branwen J. Hennig,Jonathan P. Bradfield,Beate St Pourcain,David M. Evans,Pimphen Charoen,Pimphen Charoen,Marika Kaakinen,Diana L. Cousminer,Terho Lehtimäki,Eskil Kreiner-Møller,Nicole M. Warrington,Mariona Bustamante,Bjarke Feenstra,Diane J. Berry,Elisabeth Thiering,Thiemo Pfab,Thiemo Pfab,Sheila J. Barton,Beverley M. Shields,Marjan Kerkhof,Elisabeth M. van Leeuwen,Anthony J. C. Fulford,Zoltán Kutalik,Zoltán Kutalik,Jing Hua Zhao,Marcel den Hoed,Anubha Mahajan,Virpi Lindi,Liang Kee Goh,Jouke-Jan Hottenga,Ying Wu,Olli T. Raitakari,Marie Neergaard Harder,Aline Meirhaeghe,Aline Meirhaeghe,Aline Meirhaeghe,Ioanna Ntalla,Rany M. Salem,Rany M. Salem,Karen A. Jameson,Kaixin Zhou,Dorota Monies,Vasiliki Lagou,Mirna Kirin,Jani Heikkinen,Linda S. Adair,Fowzan S. Alkuraya,Ali Al-Odaib,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Ehm A. Andersson,Amanda J. Bennett,Alexandra I. F. Blakemore,Jessica L. Buxton,Jean Dallongeville,Jean Dallongeville,Jean Dallongeville,Shikta Das,Eco J. C. de Geus,Xavier Estivill,Claudia Flexeder,Philippe Froguel,Philippe Froguel,Philippe Froguel,Frank Geller,Keith M. Godfrey,Keith M. Godfrey,Frédéric Gottrand,Christopher J. Groves,Torben Hansen,Torben Hansen,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Mads V. Hollegaard,David M. Hougaard,Elina Hyppönen,Hazel Inskip,Aaron Isaacs,Aaron Isaacs,Torben Jørgensen,Christina Kanaka-Gantenbein,John P. Kemp,Wieland Kiess,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Norman Klopp,Bridget A. Knight,Christopher W. Kuzawa,George McMahon,John P. Newnham,Harri Niinikoski,Ben A. Oostra,Louise Pedersen,Dirkje S. Postma,Susan M. Ring,Fernando Rivadeneira,Neil R. Robertson,Sylvain Sebert,Sylvain Sebert,Olli Simell,Torsten Slowinski,Carla M. T. Tiesler,Anke Tönjes,Allan Vaag,Allan Vaag,Jorma Viikari,Jacqueline M. Vink,Nadja Hawwa Vissing,Nicholas J. Wareham,Gonneke Willemsen,Daniel R. Witte,Haitao Zhang,Jianhua Zhao,James F. Wilson,Michael Stumvoll,Andrew M. Prentice,Brian F. Meyer,Ewan R. Pearson,Colin Boreham,Cyrus Cooper,Matthew W. Gillman,George Dedoussis,Luis A. Moreno,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Maiju Saarinen,Karen L. Mohlke,Dorret I. Boomsma,Seang-Mei Saw,Seang-Mei Saw,Timo A. Lakka,Antje Körner,Ruth J. F. Loos,Ken K. Ong,Peter Vollenweider,Cornelia M. van Duijn,Gerard H. Koppelman,Andrew T. Hattersley,John W. Holloway,Berthold Hocher,Joachim Heinrich,Chris Power,Mads Melbye,Mònica Guxens,Craig E. Pennell,Klaus Bønnelykke,Hans Bisgaard,Johan G. Eriksson,Elisabeth Widen,Hakon Hakonarson,André G. Uitterlinden,Anneli Pouta,Anneli Pouta,Debbie A Lawlor,George Davey Smith,Timothy M. Frayling,Mark I. McCarthy,Mark I. McCarthy,Struan F.A. Grant,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Nicholas J. Timpson,Inga Prokopenko,Rachel M. Freathy,Rachel M. Freathy +174 more
TL;DR: The number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking, are extended and highlight genetic links between fetal growth and postnatal growth and metabolism.