R
Ronald S. Veazey
Researcher at Tulane University
Publications - 41
Citations - 7497
Ronald S. Veazey is an academic researcher from Tulane University. The author has contributed to research in topics: Simian immunodeficiency virus & Virus. The author has an hindex of 27, co-authored 30 publications receiving 7238 citations. Previous affiliations of Ronald S. Veazey include Harvard University.
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Journal ArticleDOI
Gastrointestinal Tract as a Major Site of CD4+ T Cell Depletion and Viral Replication in SIV Infection
Ronald S. Veazey,Mary Ann DeMaria,Laura V. Chalifoux,Daniel E. Shvetz,Douglas R. Pauley,Heather Knight,Michael Rosenzweig,R. Paul Johnson,Ronald C. Desrosiers,Andrew A. Lackner +9 more
TL;DR: The intestine appears to be a major target for SIV replication and the major site of CD4+ T cell loss in early SIV infection.
Journal ArticleDOI
Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells.
Zhiqiang Zhang,T. Schuler,Mary Zupancic,Stephen W. Wietgrefe,Katherine Staskus,Keith A. Reimann,Todd A. Reinhart,Michael J. Rogan,Winston Cavert,Christopher J. Miller,Ronald S. Veazey,Daan W. Notermans,Susan J. Little,Sven A. Danner,Douglas D. Richman,Douglas D. Richman,Diane V. Havlir,Joseph K. Wong,Joseph K. Wong,H. L. Jordan,Timothy W. Schacker,Paul Racz,Klara Tenner-Racz,Norman L. Letvin,Steven M. Wolinsky,Ashley T. Haase +25 more
TL;DR: Both viruses were found to replicate predominantly in CD4(+) T cells at the portal of entry and in lymphoid tissues, and infection was propagated not only in activated and proliferating T cells but also, surprisingly, in resting T cells.
Journal ArticleDOI
A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys.
Keith A. Reimann,J T Li,Ronald S. Veazey,Matilda Halloran,In-Woo Park,Gunilla B. Karlsson,Joseph Sodroski,Norman L. Letvin +7 more
TL;DR: It is shown that after two serial in vivo passages by intravenous blood inoculation of naive rhesus monkeys, this SHIV (SHIV-89.6P) induced CD4 lymphopenia and an AIDS-like disease with wasting and opportunistic infections.
Journal ArticleDOI
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
Ronald S. Veazey,Robin J. Shattock,Melissa Pope,J. Christian Kirijan,Jennifer Jones,Qinxue Hu,Tom Ketas,Preston A. Marx,Per Johan Klasse,Dennis R. Burton,John P. Moore +10 more
TL;DR: It is described here how vaginal administration of the broadly neutralizing human monoclonal antibody b12 can protect macaques from simian-human immunodeficiency virus (SHIV) infection through the vagina, and observations support the concept that viral entry inhibitors can help prevent the sexual transmission of HIV-1 to humans.
Journal ArticleDOI
Progesterone implants enhance SIV vaginal transmission and early virus load
Preston A. Marx,A I Spira,A I Spira,A Gettie,Peter J. Dailey,Ronald S. Veazey,Andrew A. Lackner,C J Mahoney,Christopher J. Miller,L E Claypool,David D. Ho,Nancy J. Alexander +11 more
TL;DR: This study shows that SIV genital infection and disease course are enhanced by subcutaneous implants containing progesterone when compared with the rate of vaginal transmission in the follicular phase.