S
Sarah Diehl
Researcher at Max Planck Society
Publications - 7
Citations - 2888
Sarah Diehl is an academic researcher from Max Planck Society. The author has contributed to research in topics: Viral replication & Hepatitis C virus. The author has an hindex of 5, co-authored 7 publications receiving 2110 citations.
Papers
More filters
Journal ArticleDOI
deepTools: a flexible platform for exploring deep-sequencing data
TL;DR: A Galaxy based web server for processing and visualizing deeply sequenced data, called deepTools, that enables users with little bioinformatic background to explore the results of their sequencing experiments in a standardized setting and can be used without registration.
Journal ArticleDOI
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment
Simon Reiss,Ilka Rebhan,Perdita Backes,Inés Romero-Brey,Holger Erfle,Petr Matula,Petr Matula,Petr Matula,Lars Kaderali,Marion Poenisch,Hagen Blankenburg,Marie Sophie Hiet,Thomas Longerich,Sarah Diehl,Fidel Ramírez,Tamas Balla,Karl Rohr,Karl Rohr,Artur Kaul,Sandra Bühler,Rainer Pepperkok,Thomas Lengauer,Mario Albrecht,Roland Eils,Roland Eils,Peter Schirmacher,Volker Lohmann,Ralf Bartenschlager +27 more
TL;DR: Analysis suggests that the direct activation of a lipid kinase by HCV NS5A contributes critically to the integrity of the membranous viral replication complex.
Journal ArticleDOI
Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program
Rossana Foti,Stefano Gnan,Daniela Cornacchia,Vishnu Dileep,Aydan Bulut-Karslioglu,Sarah Diehl,Andreas Buness,Felix A. Klein,Wolfgang Huber,Ewan Johnstone,Remco Loos,Paul Bertone,Paul Bertone,David M. Gilbert,Thomas Manke,Thomas Jenuwein,Sara C. B. Buonomo +16 more
TL;DR: It is shown that in mouse embryonic stem cells, Rif1 coats late-replicating domains and, with Lamin B1, identifies most of the late-Replicating genome.
Journal ArticleDOI
Heterochromatin boundaries are hotspots for de novo kinetochore formation
Agata M. Olszak,Dominic van Essen,António J. Pereira,Sarah Diehl,Thomas Manke,Helder Maiato,Helder Maiato,Simona Saccani,Patrick Heun +8 more
TL;DR: It is demonstrated that CID islands represent functional ectopic kinetochores, which are non-randomly distributed on the chromosome and show a preferential localization near telomeres and pericentric heterochromatin in transcriptionally silent, intergenic chromatin domains.
Journal ArticleDOI
MOF maintains transcriptional programs regulating cellular stress response
Bilal N. Sheikh,W Bechtel-Walz,Jacopo Lucci,O Karpiuk,I Hild,Björn Hartleben,Julia Vornweg,Martin Helmstädter,Abdullah H. Sahyoun,Vivek Bhardwaj,Thomas Stehle,Sarah Diehl,Oliver Kretz,Oliver Kretz,Anne K. Voss,Anne K. Voss,Tim Thomas,Tim Thomas,Thomas Manke,Tobias B. Huber,Tobias B. Huber,Asifa Akhtar +21 more
TL;DR: This work identifies MOF as a key regulator of cellular stress response in glomerular podocytes and uncovers several MOF-regulated pathways required for stress response.