S
Sergio G. Munoz-Jimenez
Publications - 6
Citations - 144
Sergio G. Munoz-Jimenez is an academic researcher. The author has contributed to research in topics: Population & IRF6. The author has an hindex of 4, co-authored 5 publications receiving 132 citations.
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Journal ArticleDOI
Strong Association of Variants around FOXE1 and Orofacial Clefting
Kerstin U. Ludwig,Anne C. Böhmer,Michele Rubini,Peter A. Mossey,Stefan Herms,Stefan Herms,Stefanie Nowak,Heiko Reutter,Heiko Reutter,Margrieta A. Alblas,B. Lippke,Sandra Barth,Mario Paredes-Zenteno,Sergio G. Munoz-Jimenez,Rocio Ortiz-Lopez,Thomas Kreusch,Alexander Hemprich,Markus Martini,Bert Braumann,Andreas Jäger,Bernd Pötzsch,Anne M. Molloy,Borut Peterlin,Peter Hoffmann,Peter Hoffmann,Markus M. Nöthen,Augusto Rojas-Martinez,Michael Knapp,Régine P.M. Steegers-Theunissen,Régine P.M. Steegers-Theunissen,E. Mangold +30 more
TL;DR: The results strongly support the FOXE1 locus as a risk factor for nsOFC in 2 independent samples of differing ethnicities.
Journal ArticleDOI
Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population: Evidence for IRF6 and variants at 8q24 and 10q25
Augusto Rojas-Martinez,Heiko Reutter,Oscar F. Chacon-Camacho,Rafael B. R. León-Cachón,Sergio G. Munoz-Jimenez,Stefanie Nowak,Jessica Becker,Ruth Herberz,Kerstin U. Ludwig,Mario Paredes-Zenteno,Abelardo Arizpe-Cantú,Susanne Raeder,Stefan Herms,Rocio Ortiz-Lopez,Michael Knapp,Per Hoffmann,Markus M. Nöthen,Elisabeth Mangold +17 more
TL;DR: It is suggested that IRF6 and the 10q25 and 8q24 loci confer a risk for the development of NSCL/P in persons of Mayan origin.
Journal ArticleDOI
Evaluating eight newly identified susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population.
Kerstin U. Ludwig,Philipp Wahle,Heiko Reutter,Heiko Reutter,Mario Paredes-Zenteno,Sergio G. Munoz-Jimenez,Rocio Ortiz-Lopez,Anne C. Böhmer,Peter Tessmann,Stefanie Nowak,Markus M. Nöthen,Michael Knapp,Augusto Rojas-Martinez,Elisabeth Mangold +13 more
TL;DR: It is suggested that the majority of the known NSCL/P susceptibility regions identified to date also confer risk for this malformation in the Mesoamerican population.
Journal ArticleDOI
Interethnic relationships of CYP2D6 variants in native and Mestizo populations sharing the same ecosystem
Yadira X. Perez-Paramo,Francisco Hernandez-Cabrera,Pedro Dorado,Adrián LLerena,Sergio G. Munoz-Jimenez,Rocio Ortiz-Lopez,Augusto Rojas-Martinez +6 more
TL;DR: Sharing of CYP2D6 alleles in both Chiapanecan populations suggests an ongoing gene-flow, and principal component analyses demonstrated clustering of both Mestizo populations.
Journal ArticleDOI
Evaluating SKI as a candidate gene for non-syndromic cleft lip with or without cleft palate.
Elisabeth Mangold,Heiko Reutter,Rafael B. R. León-Cachón,Kerstin U. Ludwig,Stefan Herms,Oscar F. Chacon-Camacho,Rocio Ortiz-Lopez,Mario Paredes-Zenteno,Abelardo Arizpe-Cantú,Sergio G. Munoz-Jimenez,Stefanie Nowak,Franz Josef Kramer,Thomas F. Wienker,Thomas F. Wienker,Markus M. Nöthen,Michael Knapp,Augusto Rojas-Martinez,Augusto Rojas-Martinez +17 more
TL;DR: The data provide limited support for the hypothesis that common SKI variants are susceptibility factors for NSCL/P, and genotypic data from two recent genome-wide association studies detected a trend toward association in the European population.