Séverine Durand

TL;DR: In this paper, a large-scale dataset of tens of thousands of units in six cortical and two thalamic regions in the brains of mice responding to a battery of visual stimuli is presented.

TL;DR: A comparative survey of receptive field properties in dLGN, lateral posterior nucleus, and V1 in anesthetized and awake mice found multiple differences in processing of time-varying stimuli, whereas the spatial aspects of receptive fields remain comparatively unchanged.

TL;DR: A large, open dataset that surveys spiking from units in six cortical and two thalamic regions responding to a battery of visual stimuli finds that inter-area functional connectivity mirrors the anatomical hierarchy from the Allen Mouse Brain Connectivity Atlas and provides a foundation for understanding coding and dynamics in the mouse cortico-thalamic visual system.

TL;DR: A biophysically detailed circuit model of layer 4 in the mouse primary visual cortex, receiving thalamo-cortical visual inputs is released, demonstrating the importance of functional rules of cortical wiring and enabling a next generation of data-driven models of in vivo neural activity and computations.

TL;DR: Comparing evoked responses in visual cortex recorded in awake mice under highly standardized conditions using either imaging or electrophysiology establishes the dominant impacts of the two modalities’ respective biases on a set of functional metrics that are fundamental for characterizing sensory-evoked responses.