Simon G. Gregory

TL;DR: Single cell RNA-Seq is performed to analyze the transcriptional heterogeneity of RBCs from three adult healthy donors which have been stored in the blood bank conditions and assayed at day 1 and day 15 to indicate the power of single RBC RNA- Seq to capture and discover known and unexpected heterogeneity ofRBC population.

TL;DR: In this paper, a competition between PTBP1 and U2AF2 at the polypyrimidine tract (PPT) of intron 5 was found to increase skipping of the exon, resulting in elevated levels of sIL7R.

TL;DR: In this paper, the authors presented methods of identifying a subject having an increased or decreased risk of developing cardiovascular disease, comprising of correlating the presence of one or more genetic markers in chromosome 3q13.31 with an increased risk of cardiovascular disease; and detecting the one or multiple genetic markers of step (a) in the subject.

TL;DR: Evaluated LSAMP SNP-specific hazards for all-cause mortality post-catheterization in a larger cohort of the authors' CAD cases and performed additional replication in an independent dataset suggest that genetic effects of rs1462845 on survival are unique to CAD presence.