S
Sofie Bekaert
Researcher at Ghent University
Publications - 77
Citations - 3684
Sofie Bekaert is an academic researcher from Ghent University. The author has contributed to research in topics: Population & Telomere. The author has an hindex of 29, co-authored 77 publications receiving 3300 citations. Previous affiliations of Sofie Bekaert include Ghent University Hospital.
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Journal ArticleDOI
Gender and telomere length : systematic review and meta-analysis
Michael P. Gardner,David Bann,Laura Wiley,Rachel Cooper,Rebecca Hardy,Dorothea Nitsch,Carmen Martin-Ruiz,Paul G. Shiels,Avan Aihie Sayer,Michelangela Barbieri,Sofie Bekaert,Claus Bischoff,Angela Brooks-Wilson,Wei Chen,Cyrus Cooper,Kaare Christensen,Tim De Meyer,Ian J. Deary,Geoff Der,Ana V. Diez Roux,Annette L. Fitzpatrick,Anjum Hajat,Julius Halaschek-Wiener,Sarah E. Harris,Steven C. Hunt,Carol Jagger,Hyo Sung Jeon,Robert C. Kaplan,Masayuki Kimura,Peter M. Lansdorp,Changyong Li,Toyoki Maeda,Massimo Mangino,Tim S. Nawrot,Peter M. Nilsson,Katarina Nordfjäll,Giuseppe Paolisso,Fu Ren,Karl Riabowol,Tony Robertson,Göran Roos,Jan A. Staessen,Tim D. Spector,Nelson L.S. Tang,Brad M. Unryn,Pim van der Harst,Jean Woo,Chao Xing,Mohammad E Yadegarfar,Jae Yong Park,Neal S. Young,Diana Kuh,Thomas von Zglinicki,Yoav Ben-Shlomo +53 more
TL;DR: Telomere length is longer in females than males, although this difference was not universally found in studies that did not use Southern blot methods, and further research on explanations for the methodological differences is required.
Journal ArticleDOI
Telomere length and cardiovascular risk factors in a middle‐aged population free of overt cardiovascular disease
Sofie Bekaert,Tim De Meyer,Ernst Rietzschel,Marc De Buyzere,Dirk De Bacquer,Michel Langlois,Patrick Segers,Luc Cooman,Piet Van Damme,Peter Cassiman,Wim Van Criekinge,Pascal Verdonck,Guy De Backer,Thierry C. Gillebert,Patrick Van Oostveldt +14 more
TL;DR: It is shown that TL of peripheral blood leukocytes primarily reflects the burden of increased oxidative stress and inflammation, whether or not determined by an increasingly unhealthy lifestyle, while the association with classical CVD risk factors is limited.
Journal ArticleDOI
NMR-Based Characterization of Metabolic Alterations in Hypertension Using an Adaptive, Intelligent Binning Algorithm
Tim De Meyer,Davy Sinnaeve,Björn Van Gasse,Elena Tsiporkova,Ernst Rietzschel,Marc De Buyzere,Thierry C. Gillebert,Sofie Bekaert,José C. Martins,Wim Van Criekinge +9 more
TL;DR: The binning algorithm resulted in an improved classification of hypertensive status compared with that of standard binning and facilitated the identification of relevant metabolites, and the involvement of alpha-1 acid glycoproteins and choline biochemistry in hypertension is suggested.
Journal ArticleDOI
PubMeth: a cancer methylation database combining text-mining and expert annotation
Maté Ongenaert,Leander Van Neste,Tim De Meyer,Gerben Menschaert,Sofie Bekaert,Wim Van Criekinge +5 more
TL;DR: PubMeth is a cancer methylation database that includes genes that are reported to be methylated in various cancer types that is based on text-mining of Medline/PubMed abstracts, combined with manual reading and annotation of preselected abstracts.
Journal ArticleDOI
Amplification of the Pressure Pulse in the Upper Limb in Healthy, Middle-Aged Men and Women
Patrick Segers,Dries Mahieu,Jan Kips,Ernst Rietzschel,Marc De Buyzere,Dirk De Bacquer,Sofie Bekaert,Gui De Backer,Thierry C. Gillebert,Pascal Verdonck,Lucas Van Bortel +10 more
TL;DR: It is concluded that, in healthy middle-aged subjects, the central-to-radial amplification of the pressure pulse is substantial, higher in men than in women, decreases with age, and is primarily associated with the carotid augmentation index.