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Song Liu

Researcher at Roswell Park Cancer Institute

Publications -  195
Citations -  4183

Song Liu is an academic researcher from Roswell Park Cancer Institute. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 29, co-authored 193 publications receiving 2962 citations. Previous affiliations of Song Liu include National Institute of Standards and Technology & Nokia.

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Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

Daniel K. Wells, +149 more
- 29 Oct 2020 - 
TL;DR: A model of tumor epitope immunogenicity was developed that filtered out 98% of non-immunogenic peptides with a precision above 0.70 and was validated in an independent cohort of 310 epitopes prioritized from tumor sequencing data and assessed for T cell binding.
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A Gynecologic Oncology Group study of frequent copy number aberrations in DNA repair genes and other genomic regions in stage I serous ovarian cancers

TL;DR: Several genes associated with the Fanconi DNA-damage response pathway were frequently altered in stage I serous ovarian carcinomas and the GOG-0175 virtual tissue bank yielded high quality DNA for detecting and mapping CNAs in archival FFPE specimens with high resolution.
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Computational methods for detecting copy number variations in cancer genome using next generation sequencing: principles and challenges.

TL;DR: This review aims to provide a guide to the analytic tools used in NGS-based cancer CNV studies, and to discuss the important factors that researchers need to consider when analyzing NGS data for somatic CNV detections.
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Efficacy and Safety of Pembrolizumab in Combination With Bevacizumab and Oral Metronomic Cyclophosphamide in the Treatment of Recurrent Ovarian Cancer: A Phase 2 Nonrandomized Clinical Trial

TL;DR: In this phase 2 nonrandomized clinical trial, the combination of pembrolizumab with bevacizumAB and oral cyclophosphamide was well tolerated and demonstrated clinical benefit in 95.0% and durable treatment responses in 25.0%" of patients with recurrent ovarian cancer.
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JunB contributes to Id2 repression and the epithelial-mesenchymal transition in response to transforming growth factor-β.

TL;DR: JunB helps set in motion the transcriptional program necessary for the epithelial–mesenchymal transition and tissue fibrosis in response to TGF-β.