S
Surjeet Singh
Researcher at University of Oxford
Publications - 13
Citations - 883
Surjeet Singh is an academic researcher from University of Oxford. The author has contributed to research in topics: Giant cell arteritis & Biopsy. The author has an hindex of 8, co-authored 13 publications receiving 762 citations. Previous affiliations of Surjeet Singh include University of Birmingham.
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Journal ArticleDOI
A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids
Martin L. Read,Surjeet Singh,Zubair Ahmed,Mark Stevenson,Simon S. Briggs,David Oupicky,Lee Barrett,Rachel Spice,Mark A. F. Kendall,Martin Berry,Jon A. Preece,Ann Logan,Leonard W. Seymour +12 more
TL;DR: Results demonstrate that HIS RPCs represent a novel and versatile type of vector that can be used for efficient cytoplasmic delivery of a broad range of nucleic acids.
Journal ArticleDOI
The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis (TABUL): a diagnostic accuracy and cost-effectiveness study.
Raashid Luqmani,Ellen Lee,Surjeet Singh,M Gillett,Wolfgang A. Schmidt,Mike Bradburn,Bhaskar Dasgupta,Andreas P. Diamantopoulos,Wulf Forrester-Barker,William Hamilton,Shauna Masters,Brendan McDonald,Eugene McNally,Colin T. Pease,Jennifer Piper,John F Salmon,Allan Wailoo,Konrad Wolfe,Andrew Hutchings +18 more
TL;DR: The feasibility of providing training in ultrasound for the diagnosis of giant cell arteritis has been demonstrated and the results indicate better sensitivity but poorer specificity of ultrasound compared with biopsy and suggest some scope for reducing the role of biopsy.
Journal ArticleDOI
Delivery of siRNA mediated by histidine-containing reducible polycations.
Mark Stevenson,Victor Ramos-Perez,Surjeet Singh,Mahmoud E. S. Soliman,Jon A. Preece,Simon S. Briggs,Martin L. Read,Leonard W. Seymour +7 more
TL;DR: Incorporation of a targeting peptide from the Plasmodium falciparum circumsporozoite protein onto His6 RPCs significantly improved transfection of plasmid DNA and siRNA activity in hepatocytes, but not in most non-liver cells tested.
Journal ArticleDOI
Partial ablation versus radical prostatectomy in intermediate-risk prostate cancer: the PART feasibility RCT
Freddie C. Hamdy,Daisy Elliott,S. Le Conte,Lucy Davies,Richéal Burns,C Thomson,Richard Gray,Jane Wolstenholme,Jenny L Donovan,Jenny L Donovan,Ray Fitzpatrick,Clare Verrill,Fergus V. Gleeson,Surjeet Singh,Derek J. Rosario,James W.F. Catto,Simon Brewster,Tim Dudderidge,Richard Hindley,A. Emara,P Sooriakumaran,Hashim U. Ahmed,Tom Leslie +22 more
TL;DR: A prospective, multicentre, open-label feasibility study to inform the design and conduct of a future RCT of PA using high-intensity focused ultrasound (HIFU) versus radical prostatectomy (RP) for intermediate-risk PCa and to test and optimise methods of data capture.
Journal ArticleDOI
(LYS) 16 -based reducible polycations provide stable polyplexes with anionic fusogenic peptides and efficient gene delivery to post mitotic cells
TL;DR: It is concluded that (Lys)(16)-based RPC/DNA/fusogenic peptide particles provide a gene delivery system which is potentially stable in the extracellular environment and, on reductive depolymerisation, can release DNA plasmids for nuclear translocation.