T
Thomas D. Schmittgen
Researcher at University of Florida
Publications - 119
Citations - 177830
Thomas D. Schmittgen is an academic researcher from University of Florida. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 48, co-authored 111 publications receiving 150512 citations. Previous affiliations of Thomas D. Schmittgen include University of Southern California & University of Oklahoma.
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Journal ArticleDOI
Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia
Lais Da Silva,Jinmai Jiang,Corey M. Perkins,Kalina R. Atanasova,Julie K. Bray,Gamze B. Bulut,Ana Clara P. Azevedo-Pouly,Martha Campbell-Thompson,Xiaozhi Yang,Hesamedin Hakimjavadi,Srikar Chamala,Ranjala Ratnayake,Raad Z. Gharaibeh,Chenglong Li,Hendrik Luesch,Thomas D. Schmittgen +15 more
TL;DR: In this paper , the effects of a novel pStat3 inhibitor (LLL12B) and the histone deacetylase (HDAC) inhibitor trichostatin A (TSA) were investigated using 3-D cultures from p48Cre/+ and p48 Cre/+LSL-KrasG12D/+ (KC) mice.
Journal ArticleDOI
Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia
Lais Da Silva,Jinmai Jiang,Corey M. Perkins,Kalina R. Atanasova,Julie K. Bray,Gamze Bulut,Ana Clara P. Azevedo-Pouly,Martha Campbell-Thompson,Xiaozhi Yang,Hesamedin Hakimjavadi,Srikar Chamala,Ranjala Ratnayake,Raad Z. Gharaibeh,Chenglong Li,Hendrik Luesch,Thomas D. Schmittgen +15 more
TL;DR: In this article , the effects of a novel pStat3 inhibitor (LLL12B) and the histone deacetylase (HDAC) inhibitor trichostatin A (TSA) were investigated using 3-D cultures from p48Cre/+ and p48 Cre/+LSL-KrasG12D/+ (KC) mice.
Journal ArticleDOI
Alterations in mouse spinal cord and sciatic nerve microRNAs after the chronic constriction injury (CCI) model of neuropathic pain.
Jenny L. Wilkerson,Jinmai Jiang,Jasmine S. Felix,Julie K. Bray,Lais Da Silva,Raad Z. Gharaibeh,Lance R. McMahon,Thomas D. Schmittgen +7 more
TL;DR: The data support miRNAs as promising therapeutic targets for the treatment of pathological pain and help elucidate potential biomarkers relevant to pathological pain in humans.
Journal ArticleDOI
Retraction notice to "Human chromosome 21-derived miRNAs are over-expressed in down syndrome brains and hearts" [Biochem. Biophys. Res. Commun. 370 (2008) 473-477]
Donald E. Kuhn,Gerard J. Nuovo,Mickey M. Martin,Geraldine E. Malana,Adam Pleister,Jinmai Jiang,Thomas D. Schmittgen,Alvin V. Terry,Katheleen Gardiner,Elizabeth Head,David S. Feldman,Terry S. Elton +11 more
Journal ArticleDOI
Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants.
Thomas D. Schmittgen,Antoinette Koolemans-Beynen,Thomas E. Webb,Thomas J. Rosol,Jessie L.-S. Au +4 more
TL;DR: The data indicate that the IC values for FU are comparable in tumor explants and in rats, suggesting that the effects in cultured tumors reflect those in intact animals.