T
Thomas Powles
Researcher at Queen Mary University of London
Publications - 804
Citations - 57482
Thomas Powles is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 82, co-authored 655 publications receiving 39271 citations. Previous affiliations of Thomas Powles include Charing Cross Hospital & University of London.
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Journal ArticleDOI
1752P Post hoc analysis of pembrolizumab efficacy in potentially platinum ineligible patients with urothelial carcinoma enrolled in KEYNOTE-052 and LEAP-011
Yohann Loriot,Tibor Csőszi,Naoko Matsubara,Sun-Jeong Shin,S.-H. Park,Vagif A. Atduev,Mahmut Gumus,Burhan Karaca,Petros Grivas,Ronald de Wit,Arlene O. Siefker-Radtke,D. Castellano Gauna,Peter H. O'Donnell,Thomas Powles,Jacqueline Vuky,Y Zhao,Karen O'Hara,Sonia Franco,Blanca Homet Moreno,Jakub Zolnierek +19 more
TL;DR: In this article , the efficacy of pembrolizumab in UC varies based on criteria used to define platinum ineligibility, but there is no standard definition of platinum-ineligible patients with advanced UC in the US.
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Rise of Antibody-Drug Conjugates: The Present and Future.
TL;DR: The most successful application for solid tumors has been in breast cancer, with ADCs becoming the standard of care across traditional human epidermal growth factor receptor 2 (HER2)+, hormone receptor+ (HR+) and triple-negative disease subtypes as discussed by the authors .
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Study EV-104: Phase 1 study of intravesical enfortumab vedotin for treatment of patients with Non-Muscle Invasive Bladder Cancer (NMIBC) (Trial in Progress)
Ashish M. Kamat,GD Steinberg,Brant A. Inman,Max Kates,Edward Uchio,Sima P. Porten,M. Rouperet,Joan Palou,James W.F. Catto,GS Kulkarni,Thomas Powles,Mark D. Tyson,G. Haas,Xiang Ding,Saishalini Chinnathambi Narayanan,Yair Lotan +15 more
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Reply To Kenneth B. Yatai, Mark J. Dunning, Dennis Wang. Consensus Genomic Subtypes of Muscle-invasive Bladder Cancer: A Step in the Right Direction but Still a Long Way To Go. Eur Urol 2020;77:434-5.
Aurélie Kamoun,Aurélien de Reyniès,Yves Allory,Gottfrid Sjödahl,A. Gordon Robertson,Roland Seiler,Katherine A. Hoadley,Clarice S. Groeneveld,Hikmat Al-Ahmadie,Woonyoung Choi,Mauro A. A. Castro,Jacqueline Fontugne,Pontus Eriksson,Qianxing Mo,Jordan Kardos,Alexandre R. Zlotta,Arndt Hartmann,Colin P.N. Dinney,Joaquim Bellmunt,Thomas Powles,Núria Malats,Keith S. Chan,William Y. Kim,David J. McConkey,Peter C. Black,Lars Dyrskjøt,Mattias Höglund,Seth P. Lerner,Francisco X. Real,François Radvanyi,Mattias Aine,Isabelle Bernard-Pierrot,Bogdan Czerniak,Ewan A. Gibb,Jaegil Kim,David J. Kwiatkowski,Thierry Lebret,Fredrik Liedberg,A Arlene Siefker-Radtke,Nanor Sirab,Ann Taber,John N. Weinstein +41 more
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Immuno- versus chemo-therapy as first line treatment for advanced urothelial cancer: A systematic review and meta-analysis
Alessandra Martini,Daniele Raggi,Giuseppe Fallara,Luigi Nocera,Federico Belladelli,Laura Marandino,Andrea Salonia,Alberto Briganti,Francesco Montorsi,Thomas Powles,Andrea Necchi +10 more