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Thomas Powles
Researcher at Queen Mary University of London
Publications - 804
Citations - 57482
Thomas Powles is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 82, co-authored 655 publications receiving 39271 citations. Previous affiliations of Thomas Powles include Charing Cross Hospital & University of London.
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Journal ArticleDOI
Is there an antiandrogen withdrawal syndrome with enzalutamide
Alejo Rodriguez-Vida,Diletta Bianchini,Mieke Van Hemelrijck,Simon Hughes,Zafar Malik,Thomas Powles,Amit Bahl,Sarah Rudman,Heather Payne,Johann S. de Bono,Simon Chowdhury +10 more
TL;DR: To examine prostate‐specific antigen (PSA) levels after enzalutamide discontinuation to assess whether an antiandrogen withdrawal syndrome (AAWS) exists with enzalUTamide.
Journal ArticleDOI
Immune Checkpoint Inhibition in Metastatic Urothelial Cancer
TL;DR: Predictive biomarkers are needed to go beyond PD-L1 expression, which is showing inconsistent results across trials.
Journal ArticleDOI
Axitinib plus immune checkpoint inhibitor: evidence- and expert-based consensus recommendation for treatment optimisation and management of related adverse events.
Viktor Grünwald,Martin H. Voss,Brian I. Rini,Thomas Powles,Laurence Albiges,Rachel H. Giles,Eric Jonasch +6 more
TL;DR: This work addressed areas of AEs requiring unique management during treatment with axitinib–ICI combinations that were not covered by current recommendations and focused on AEs with an overlap between axit inib and ICI therapy.
Journal ArticleDOI
Imaging in Suspected Renal-Cell Carcinoma : Systematic Review
Christina Vogel,Brigitte Ziegelmüller,Börje Ljungberg,Karim Bensalah,Axel Bex,Steven E. Canfield,Rachel H. Giles,Milan Hora,Markus A. Kuczyk,Axel S. Merseburger,Thomas Powles,Laurence Albiges,Fiona Stewart,Allseandro Volpe,Anno Graser,Marcus Schlemmer,Cathy Yuhong Yuan,Thomas B. Lam,Thomas B. Lam,Michael Staehler +19 more
TL;DR: The diagnosis of a renal mass should be based on contrast‐enhanced CT or MRI with the recommendation to use contrast‐ enhanced US for further differentiation in unclear renal masses.
Journal ArticleDOI
Genitourinary tumors, non-prostate
Alain Ravaud,Carlos H. Barrios,Oezlem Anak,D. Pelov,A. Louveau,Boris Alekseev,T. M-H,Sanjiv S. Agarwala,S Songül Yalçin,Bohuslav Melichar,David F. McDermott,Charles G. Drake,Mario Sznol,Toni K. Choueiri,John D. Powderly,David Smith,Jon M. Wigginton,Georgia Kollia,Ashok Kumar Gupta,Michael B. Atkins,Frede Donskov,M.D. Michaelson,Igor Puzanov,Mellar P. Davis,Georg A. Bjarnason,Robert J. Motzer,Xun Lin,Darrel P. Cohen,Robin Wiltshire,Brian I. Rini,Stéphane Oudard,Stéphane Culine,A. Vieillefond,Frank Priou,F. Goldwasser,G. Gravis-Mescam,G. Deplanque,J-P. Machiels,P. Beuzeboc,Guru Sonpavde,B. Maughan,K.M. Boucher,R. Fougeray,Günter Niegisch,Y.-N. Wong,S.S. Sridhar,Cora N. Sternberg,Joaquim Bellmunt,Christopher M. Booth,D.R. Siemens,G. Li,Yingwei Peng,I.F. Tannock,David M. Berman,W. Kong,W.J. Mackillop,F. Selle,Karim Fizazi,P. Biron,B. Bui,J. Bay,A. Flechon,C. Dubot,A. Caty,D. Burcoveanu,R. Delva,T. de Revel,J.M. Miclea,M. Gaulet,E. Horn,S. Provent,I. Temby,I. Brindel,J. Khalil,J. Gligorov,J.-P. Lotz,David I. Quinn,Omid Hamid,Denice D. Tsao-Wei,J. Hu,Jacek Pinski,Anne Schuckman,Siamak Daneshmand,Susan Groshen,Derek Raghavan,C. Korn,K. Massopust,C. Ketchens,A.M. Aparicio,Tanya B. Dorff,A. Zurita-Saavedra,Yuan Liu,Y. Lin,Hai T. Tran,Veg Team,investigators,L.N. Pandite,J.V. Heymach,David Cella,K. Kaiser,J. Beaumont,Javier Diaz,L. McCann,F. Mehmud,S. Lata,Petri Bono,C. Porta,B. Escudier,Piotr Tomczak,Sylvie Negrier,M.E. Gore,Jamal Tarazi,Subramanian Hariharan,Brad Rosbrook,Sinil Kim,T.E. Hutson,G.R. Hudes,R.A. Figlin,J.-F. Martini,Patricia A. English,L. Wood,Xin-Yun Huang,Olga Valota,J.A. Williams,T. Eisen,M. Harza,Viorel Jinga,B. Esteves,D. Nosov,J. Loewy,L. Hodge,A. Berkenblit,W. Yin,K. Dykstra,M. Cotreau,M. De Fromont,C. Chevreau,Gwenaelle Gravis,S. Zanetta,C. Theodore,M. Jimenez,E. Sevin,Sergio Bracarda,J. P. Maroto,C. Szczylik,Paul Nathan,K. Slimane,C. May,Viktor Grünwald,J.A. Arranz Arija,R. Mondéjar Solís,M.P. López Martí,P. Sabin Domínguez,M.C. Lopez Lopez,G. Tapia Rico,B. Moya Ortega,D. Urosa Velasco,E. López Juarez,R. González Beca,B. Biswas,R.K. Sahoo,L. Kumar,B.K. Mohanti,A. Seth,W. Arafat,A. Darwish,G. El Hussiny,J.L. Cuadra Urteaga,M. Domenech,P. Celiz,J.J. Sánchez,N. Pardo,C. Buges,J. Malet,M. Arzoz,J. Areal,A. Font,G. Elhussiny,G.R. Pond,Walter M. Stadler,C. De La Piedra,E. Esteban,M. Climent,B. González,J.L. Álvarez-Ossorio,I. Chirivella Gonzalez,Begoña Mellado,P.C. Lara,A. Alcaraz,J. Carles,Pablo Maroto,R. Morales-Barrera,Cristina Suarez,C. Martin Lorente,O. Etxaniz,L. Capdevila,Daniel Castellano,M. Taron,I. Chaib,P. Mendez,B. Sanchez,R. Rosell,Robert E. Hawkins,V. Galvis,A. Shablak,A. Spencer-Shaw,Fiona C Thistlethwaite,J. Shanks,N. Dalal,Vsevolod Matveev,A. Kaprin,R. Janciauskiene,B. Lutiger,G. Mickisch,Y. Su,N. Shi,P. Landsman-Blumberg,C. Poehlein,I. Waxman,Mayer Fishman,M. Carducci,A. Bair,Ying Chen,L. Bodnar,R. Stec,M. Cichowicz,S. Cierniak,M. Smoter,W. Kozłowski,I.G. Schmidt-Wolf,S. Hauser,S. Weikert,M. Schroff,M. Schmidt,E. Weith,M. Tschaika,B. Wittig,A.M. Molina,James Larkin,Anne Gold,Corina Andresen,K. Wood,Andrew G. Bushmakin,Joseph C. Cappelleri,Beata Korytowsky,Rickard Sandin,E. Matczak,J. Mardiak,J. Ma,E. Korbenfeld,M. Zemanova,N. Leonhartsberger,K. Stauch,A. Boeckenhoff,J. Yu,D. Jäger,R. Iacovelli,M. Santoni,G. Di Lorenzo,L. Cerbone,M. Aglietta,C. Masini,M.O. Giganti,C. Messina,G. Procopio,A.V. Soerensen,G.G. Hermann,N.V. Jensen,H. Spliid,E.Q. Bergan,K. Fode,P.F. Geertsen,S. Lee,L. Crino,T.M. Kim,Kolette D. Fly,Simon Chowdhury,T.B. Powles,R.J. Jones,S. Crabb,S. Sarker,E. Boleti,Jonathan Shamash,N. Sarwar,E. Calvo,R. Casciano,L. Stern,T. Brechenmacher,S. Stergiopoulos,J. Coombs,E. Verzoni,I. Testa,E. Garanzini,F. de Braud,Emilio Bria,Francesco Massari,F. Maines,M. Bonomi,Francesco Cognetti,D. Giannarelli,Giampaolo Tortora,Michele Milella,L. Anton-Aparicio,S. Vazquez-Estevez,U. Anido,F.J. Afonso,O. Fernandez,M. Lazaro,L. Santomé,M. Ramos Vazquez,Muhammad A. Khattak,Kim Edmonds,Komel Khabra,Aslam Sohaib,K. Pennert,Lisa Pickering,U. Mueller,G. Krekeler,L. Bergmann,T. Steiner,D. Kalanovic,M. Bianconi,Mario Scartozzi,Luca Faloppi,Cristian Loretelli,L. Burattini,Alessandro Bittoni,M. Del Prete,Riccardo Giampieri,R. Montironi,S. Cascinu,D. Tunali,B. Sarsık,Raika Durusoy,S. S¸en,E. Gökmen,A. Suder,Kiruthikah Thillai,S. Rudman,A. Chandra,G. Rottenberg,Ben Challacombe,G. Kooiman,P. Srinivasan,Tim O'Brien,E. Fernández-Parra,M.J. Méndez-Vidal,L. León,Begoña Perez-Valderrama,V. Calderero,J.L. Perez Gracia,F. Algaba,A.J. Zurita Saavedra,K.L. Baker-Neblett,I. Park,K.J. Park,Sook Ryun Park,Yongchel Ahn,J-H Ahn,H.J. Choi,C. Song,Heui June Ahn,J.H. Hong,Joseph K. T. Lee,J.F. Rodríguez-Moreno,M. Morente,I. Alemany,A. González del Alba,C. Rodriguez-Antona,J. Garcia-Donas,M. Rizzo,V. Lorusso,F. Atzori,P.A. Zucali,C. Sacco,F. Boccardo,F. Valduga,Laurence Albiges,F. Riet,Christophe Massard,S. Le Moulec,Yohann Loriot,Antonin Levy,Umut Demirci,M. Yaman,Suleyman Buyukberber,O. Ekinci,S. Ozkan,Ugur Coskun,Mustafa Benekli,A. Ozet,Ü.E. Bagriacik,L. Ruiz,A. Pinto,I. Duran,N. Lainez,A. Lopez,Andrea Viqueira,F. Pons Valladares,M.E. Lampron,U. Kube,J. Eymard,M. Schmidinger,A. Bamias,M. Ktiouet,G. Fischer,D. Xanthaki,G. Guderian,J. Thompson,P.F. Conte,Ashok Panneerselvam,Svetozar Gogov,D. Chen,Irina Proskorovsky,A. Benedict,C. Chen,J. Guo,M. Jebali,J. Fouque,G. Fargues,A. Jouinot,Reza Elaidi,J. Medioni,A. Felici,M. Aieta,G. Lo Re,C. Boni,E. Aitini,E. Villa,S. De Placido,Xudong Zhang,J.Y. Yuan,L. Wang,L. Chen,J. Pan,L. Ye,X. Xiao,J. Qiu,K. Zhang,G. Ye,P. Sandström,J. Kowalski,T. Wahlgren,M. Jakobsson,S. Lundstam,Börje Ljungberg,U. Harmenberg,K. Nagyivanyi,K. Bíró,F. Gyergyay,Z. Küronya,H. Nemeth,L. Géczi,J.M. Sepulveda Sanchez,C. Farfan,F. Villacampa,G. Velasco,Jose Carlos Benitez,Cristina Suarez Rodriguez,M. Calderon,I. Cañamares,H. Cortes-Funes,Shaowen Qin,J. Jin,J. Wang,F. Zhou,Y. Huang,X. Ren,D. Ye,Q. Wang,S. Pan,C. Teghom,A. Comte,O. Reig Torras,M.C. Sebastia,I. Victoria,B. Paño,Marc Campayo,C. Nicolau,M.P. Trojniak,A. Cappetta,A.C. Palozzo,S. Imbevaro,P. Rescigno,A. Jirillo,J. Kim,D. Kim,Y. Kim,D.S. Heo,I. Ozer-Stillman,R. Keyser,A. Ambavane,P. Cislo,M. Fehr,T. Geldart,H. Sun,P.D. Simmonds,G. Mead,M. Wheater,N. Nagaraj,Sally Ellis,R. von Moos,R. Cathomas,J.T. Hartmann,B. Metzner,C. Binder,H. Mergenthaler,O. Rick,H.G. Sayer,A. Lorch,W.E. Berdel,C. Bokemeyer,Thomas Gauler,A.J. McPartlin,R. Roy,D. Muskett,M. Witkowski,A.J. Birtle,Sarvendra Kumar,I.A. Muazzam,N. Muzaffar,N. Siddqui,K. Das,P. Giannatempo,A. Necchi,Maurizio Colecchia,B. Paolini,N. Nicolai,Daniele Raggi,M. Catanzaro,D. Biasoni,R. Salvioni,A.M. Gianni,C. Helissey,L. Védrine,B. Ceccaldi,A. Houlgatte,H. Mullot,O. Bauduceau,Cyrus Chargari,U. De Giorgi,G. Rosti,B. Kopf,C. Ferrario,G. Papiani,R. De Vivo,A.L. Gentile,F. Fabbri,M. Bragagni,D. Amadori,N. Bonnin,Helen Boyle,M. Rivoire,C. Bailly,J. Droz,Michal Mego,Danka Cholujova,P. Gronesova,M. Pastorek,V. Miskovska,J. Obertova,V. Usakova,D. Ondrus,S. Spanik,N. Karadurmus,A.S. Ataergin,G. Erdem,M. Cakar,I. Barista,T. Turker,S. Ozaydin,M. Ozturk,F. Arpaci,I. Bodrogi,F. Lumachi,D. Santeufemia,F. Pili,S.M. M. Basso,G. Miolo,G.B. Chiara,M. Ermani,S. Tumolo,P. Rocca Cossu,R. Rosa,V. Damiano,L. Nappi,L. Formisano,A. Scarpa,G. Martignoni,R. Bianco,A. De Both,V. Kruse,E. De Coene,N. Clottens,A. Somers,S. Van Belle,L. van Bortel,S. Rottey,S.J. Park,Dae Ho Lee,C. Kim,S. Pusceddu,R. Buzzoni,E. Bajetta,A. Damato,Hussein M. Khaled,H. Abdel Azim,E. Barsoum,G. Chahine,A. Shamseddine,G. Abdel Metaal,A. Omar,A.R. Jazeih,A. Badran,C. Kahl,L. Maute,A. Vuillemin,L. Jacobasch,J. Schmitz,A. Guillot,C. Papandreou,C. Emmanouilides,T. Nguyen,T. Montella,D. Herchenhorn,J. Neves,I. Fernandes,J. Ribeiro,D. Macedo,L. Costa,A. Onofri,V. Prati,M. Nicodemo,R. Sabbatini,F.L. Lim,P. Wilson,Thomas Powles,Lisa Derosa,L. Galli,A. Fontana,E. Biasco,R. Marconcini,C. Cianci,A. Farnesi,F. Orlandi,Alfredo Falcone,S. Babakulov,S. Navruzov,Parminder Singh,R.R. Prasad,E. Paze,F. Brusa,L. Ciuffreda,I. Chiappino,Meral Kurt,H. Ozturk,S. Cetintas,E. Kurt,L. Ozkan,Ignacio Gil-Bazo,E. Castanon Alvarez,L.E. Abella,M.E. Zudaire,A. Castillo,E. Arevalo,J.P. Fusco,J.J. Zudaire,R. Martínez-Monge,O.E. Carranza,R. Lewis,J. Chester,J. Donovan,M. Johnson,R. Kockelbergh,E. Jones,E. Hall,I.G. Sullivan,G. Anguera,C. Arqueros,D. Condori,J. Palou,J.A. Peña,H. Villavicencio,H. Pandha,M. Staehler,D.J. George,A. Pantuck,A.A. Patel,P. Gerletti,Jean Jacques Patard,M. Reckova,D. Svetlovska,Z. Sycova-Mila,P. Palacka,J. Rajec,S. Liskova,S. Hernando,L. Steelman,D. Cesic +698 more
TL;DR: Combining BEV with the mTOR inhibitor EVE may be an efficacious and well-tolerated treatment option for mRCC and PFS and tolerability were similar for first-line EVE +-BEV and IFN + BEV.