Thor Petersen

TL;DR: In this paper, the authors measured neutralising antibodies every 12 months for up to 60 months in 541 patients with multiple sclerosis, randomly selected from all patients who started treatment with interferon beta between 1996 and 1999.

TL;DR: The findings suggest that the presence of neutralising antibodies against interferon beta reduces the clinical effect of the drug, which should prompt consideration about change of treatment in patients who are not doing well on interferons beta.

TL;DR: In this article, the authors evaluated the accuracy and feasibility of an objective definition for secondary progressive multiple sclerosis, to enable comparability of future research studies, using MSBase, a large, prospectively acquired, global cohort study, and analyzed the accuracy of 576 data-derived onset definitions for SPM and compared these to a consensus opinion of three neurologists.

TL;DR: Twelve weeks of intense progressive resistance training of the lower extremities leads to improvements of muscle strength and functional capacity in patients with multiple sclerosis, the effects persisting after 12 weeks of self-guided physical activity.

TL;DR: Fatigue, mood and quality of life all improved following progressive resistance training, the beneficial effect being maintained for at least 12 weeks after end of intervention.