T
Ting-Di Wu
Researcher at Curie Institute
Publications - 49
Citations - 3409
Ting-Di Wu is an academic researcher from Curie Institute. The author has contributed to research in topics: Secondary ion mass spectrometry & Mass spectrometry. The author has an hindex of 25, co-authored 46 publications receiving 2930 citations. Previous affiliations of Ting-Di Wu include University of Paris-Sud & PSL Research University.
Papers
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Journal ArticleDOI
Mammalian heart renewal by pre-existing cardiomyocytes
Samuel E. Senyo,Matthew L. Steinhauser,Christie L Pizzimenti,Vicky K. Yang,Lei Cai,Mei Wang,Ting-Di Wu,Ting-Di Wu,Jean-Luc Guerquin-Kern,Jean-Luc Guerquin-Kern,Claude Lechene,Richard T. Lee,Richard T. Lee +12 more
TL;DR: It is found that cell cycle activity during normal ageing and after injury led to polyploidy and multinucleation, but also to new diploid, mononucleate cardiomyocytes.
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Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy).
TL;DR: The decisive capability of this new ion nanoprobe (CAMECA NanoSIMS 50), and more generally of high-resolution dynamic SIMS imaging in biology, are illustrated with the most recent examples of utilization.
Journal ArticleDOI
No Evidence for Cardiomyocyte Number Expansion in Preadolescent Mice
Kanar Alkass,Joni Panula,Mattias Westman,Ting-Di Wu,Ting-Di Wu,Jean-Luc Guerquin-Kern,Jean-Luc Guerquin-Kern,Olaf Bergmann +7 more
TL;DR: It is found that the majority of cardiomyocytes is set within the first postnatal week and that this event is followed by two waves of non-replicative DNA synthesis, which are followed by a proliferative peak in preadolescent mice.
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Simultaneous analysis of microbial identity and function using NanoSIMS.
Tianlun Li,Ting-Di Wu,Ting-Di Wu,Laurent Mazéas,Laurent Toffin,Jean-Luc Guerquin-Kern,Jean-Luc Guerquin-Kern,Gérard Leblon,Théodore Bouchez +8 more
TL;DR: In this paper, a method for simultaneous analysis of microbial identity and function is described. But the method is based on the visualization of oligonucleotide probe-conferred hybridization signal in single microbial cells and isotopic measurement using high-resolution ion microprobe (NanoSIMS).
Journal ArticleDOI
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.
Alexandre Gouzy,Gerald Larrouy-Maumus,Daria Bottai,Florence Levillain,Alexia Dumas,Joshua B. Wallach,Irène Caire-Brändli,Chantal de Chastellier,Ting-Di Wu,Renaud Poincloux,Roland Brosch,Jean-Luc Guerquin-Kern,Dirk Schnappinger,Luiz Pedro S. de Carvalho,Yannick Poquet,Olivier Neyrolles +15 more
TL;DR: This study shows that M. tuberculosis employs the asparagine transporter AnsP2 and the secreted asparaginase AnsA to assimilate nitrogen and resist acid stress through asparagus hydrolysis and ammonia release, and identifies a novel pathway to be targeted for therapeutic purposes.