Tom Dunkley

TL;DR: The localization of organelle proteins by the isotope tagging technique in conjunction with isotope tags for relative and absolute quantitation and 2D liquid chromatography for the simultaneous assignment of proteins to multiple subcellular compartments has enabled protein steady-state distributions to be determined.

TL;DR: A proteomics method for determining the subcellular localization of membrane proteins in both the endoplasmic reticulum and the Golgi apparatus in Arabidopsis using a new tool for high-throughput protein localization by isotope tagging.

TL;DR: i-Tracker allows quantitative information gained using the iTRAQ protocol to be linked with peptide identifications from popular tandem MS identification tools and hence is both a timely and useful tool for the proteomics community.

TL;DR: This work constitutes a first comprehensive systems biology study on growth-rate control in the eukaryotic cell and has direct implications for advanced studies on cell growth, in vivo regulation of metabolic fluxes for comprehensive metabolic engineering, and for the design of genome-scale systems biology models of the eUKaryoticcell.

TL;DR: A UML (unified modeling language) approach to proteomics experimental data is presented, XML and SQL (structured query language) implementations of that model are described, and capture, storage, and dissemination strategies are discussed.