U
Uko Maran
Researcher at University of Tartu
Publications - 102
Citations - 2948
Uko Maran is an academic researcher from University of Tartu. The author has contributed to research in topics: Quantitative structure–activity relationship & Molecular descriptor. The author has an hindex of 30, co-authored 99 publications receiving 2649 citations. Previous affiliations of Uko Maran include Mario Negri Institute for Pharmacological Research & University of Florida.
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Journal ArticleDOI
Structurally diverse quantitative structure--property relationship correlations of technologically relevant physical properties
Journal ArticleDOI
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression.
Tõnis Org,Francesca Chignola,Csaba Hetényi,Massimiliano Gaetani,Ana Rebane,Ingrid Liiv,Uko Maran,Luca Mollica,Matthew J. Bottomley,Giovanna Musco,Pärt Peterson +10 more
TL;DR: It is concluded that AIRE–PHD1 is an important member of a newly identified class of PHD fingers that specifically recognize H3K4me0, thus providing a new link between the status of histone modifications and the regulation of tissue‐restricted antigen expression in thymus.
Journal ArticleDOI
Interpretation of Quantitative Structure−Property and −Activity Relationships
Alan R. Katritzky,Ruslan Petrukhin,Douglas B. Tatham,Subhash C. Basak,Emilio Benfenati,Mati Karelson,Uko Maran +6 more
TL;DR: The potential utility of data reduction methods for the analysis of matrices assembled from the related properties of large sets of compounds is discussed by reference to results obtained from solvent polarity scales, ongoing work on solubilities and sweetness properties, and proposed general treatments of toxicities and gas chromatographic retention indices.
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CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity.
Kamel Mansouri,Nicole Kleinstreuer,Ahmed Abdelaziz,Domenico Alberga,Vinicius M. Alves,Vinicius M. Alves,Patrik L. Andersson,Carolina Horta Andrade,Fang Bai,Ilya A. Balabin,Davide Ballabio,Emilio Benfenati,Barun Bhhatarai,Scott Boyer,Jingwen Chen,Viviana Consonni,Sherif Farag,Denis Fourches,Alfonso T. García-Sosa,Paola Gramatica,Francesca Grisoni,Christopher M. Grulke,Huixiao Hong,Dragos Horvath,Xin Hu,Ruili Huang,Nina Jeliazkova,Jiazhong Li,Xuehua Li,Huanxiang Liu,Serena Manganelli,Giuseppe Felice Mangiatordi,Uko Maran,Gilles Marcou,Todd M. Martin,Eugene N. Muratov,Dac-Trung Nguyen,Orazio Nicolotti,Nikolai Georgiev Nikolov,Ulf Norinder,Ester Papa,Michel Petitjean,Geven Piir,Pavel V. Pogodin,Vladimir Poroikov,Xianliang Qiao,Ann M. Richard,Alessandra Roncaglioni,Patricia Ruiz,Chetan Rupakheti,Chetan Rupakheti,Sugunadevi Sakkiah,Alessandro Sangion,Karl-Werner Schramm,Chandrabose Selvaraj,Imran Shah,Sulev Sild,Lixia Sun,Olivier Taboureau,Yun Tang,Igor V. Tetko,Roberto Todeschini,Weida Tong,Daniela Trisciuzzi,Alexander Tropsha,George Van Den Driessche,Alexandre Varnek,Zhongyu Wang,Eva Bay Wedebye,Antony J. Williams,Hongbin Xie,Alexey V. Zakharov,Ziye Zheng,Richard S. Judson +73 more
TL;DR: The Collaborative Modeling Project for Androgen Receptor Activity (CoMPARA) efforts are described, which follows the steps of the Collaborative Estrogen Recept Activity Prediction Project (CERAPP).
Journal ArticleDOI
QSPR Correlation and Predictions of GC Retention Indexes for Methyl-Branched Hydrocarbons Produced by Insects
TL;DR: A successful interpretation of the complex manner by which the GC retention indexes of methylalkanes produced by insects are related to chemical structure was achieved using the quantitative structure-property relationship (QSPR) method.