U
Umesh G. Lalloo
Researcher at University of KwaZulu-Natal
Publications - 136
Citations - 9744
Umesh G. Lalloo is an academic researcher from University of KwaZulu-Natal. The author has contributed to research in topics: Tuberculosis & Population. The author has an hindex of 39, co-authored 129 publications receiving 9015 citations. Previous affiliations of Umesh G. Lalloo include University of Natal & Imperial College London.
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Journal ArticleDOI
Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa
Neel R. Gandhi,Neel R. Gandhi,Anthony P. Moll,A. Willem Sturm,Robert Pawinski,Thiloshini Govender,Umesh G. Lalloo,Kimberly Zeller,Kimberly Zeller,Jason R. Andrews,Gerald Friedland +10 more
TL;DR: MDR tuberculosis is more prevalent than previously realised in a rural area in KwaZulu Natal, South Africa and has been transmitted to HIV co-infected patients and is associated with high mortality.
Journal ArticleDOI
The burden of non-communicable diseases in South Africa.
Bongani M. Mayosi,Alan J. Flisher,Umesh G. Lalloo,Freddy Sitas,Stephen Tollman,Stephen Tollman,Debbie Bradshaw +6 more
TL;DR: The launching of a national initiative to establish sites of service excellence in urban and rural settings throughout South Africa to trial, assess, and implement integrated care interventions for chronic infectious and non-communicable diseases is urged.
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Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study
F. Van Leth,Praphan Phanuphak,Kiat Ruxrungtham,E Baraldi,S Miller,Brian Gazzard,Pedro Cahn,Umesh G. Lalloo,IP van der Westhuizen,Malan,Margaret Johnson,B R Santos,Fiona Mulcahy,Robin Wood,GC Levi,G Reboredo,Kathleen Squires,I Cassetti,D Petit,François Raffi,Christine Katlama,Robert L. Murphy,Andrej Horban,JP Dam,Elly A. M. Hassink,R. Van Leeuwen,Patrick A. Robinson,F. W. Wit,Lange Jm +28 more
TL;DR: Antiretroviral therapy with nevirapine or efavirenz showed similar efficacy, so triple-drug regimens with either NNRTI are valid for first-line treatment, there are, however, differences in safety profiles.
Journal ArticleDOI
Class-Sparing Regimens for Initial Treatment of HIV-1 Infection
Sharon A. Riddler,Richard Haubrich,A. Gregory DiRienzo,Lynne Peeples,William G. Powderly,Karin L. Klingman,Kevin W. Garren,Tania George,James F. Rooney,Barbara Brizz,Umesh G. Lalloo,Robert L. Murphy,Susan Swindells,Diane V. Havlir,John W. Mellors +14 more
TL;DR: The virologic efficacy of the NRTI-sparing regimen was similar to that of the efavirenz regimen but was more likely to be associated with drug resistance.
Journal ArticleDOI
Timing of Antiretroviral Therapy for HIV-1 Infection and Tuberculosis
Diane V. Havlir,Michelle A. Kendall,Prudence Ive,Johnstone Kumwenda,Susan Swindells,Sarojini S. Qasba,Anne F Luetkemeyer,Evelyn Hogg,James F. Rooney,Xingye Wu,Mina C. Hosseinipour,Umesh G. Lalloo,Valdilea G. Veloso,Fatuma Some,N. Kumarasamy,Nesri Padayatchi,Breno Santos,Stewart E Reid,James Hakim,Lerato Mohapi,Peter Mugyenyi,Jorge Sanchez,Javier R. Lama,Jean W. Pape,Alejandro Sanchez,Aida Asmelash,Evans Moko,Fred Sawe,Janet Andersen,Ian Sanne +29 more
TL;DR: In persons with CD4+ T-cell counts of less than 50 per cubic millimeter, earlier ART was associated with a lower rate of new AIDS-defining illnesses and death, as compared with later ART.