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Valerie C. Wasinger

Researcher at University of New South Wales

Publications -  80
Citations -  5175

Valerie C. Wasinger is an academic researcher from University of New South Wales. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 27, co-authored 74 publications receiving 4763 citations. Previous affiliations of Valerie C. Wasinger include University of Sydney & Garvan Institute of Medical Research.

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Progress with gene‐product mapping of the Mollicutes: Mycoplasma genitalium

TL;DR: A protein map of the smallest known self‐replicating organism, Mycoplasma genitalium, revealed a high proportion of acidic proteins, which allowed proteins to be identified prior to detection of their respective genes via the M. genitalium sequencing initiative.
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Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database.

TL;DR: Reverse protein to DNA matching identified proteins for 118 previously unidentified ORFs in the PPP database, and the database permits examination of many other subsets, such as 1274 proteins identified with three or more peptides.
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The dynamic range of protein expression: a challenge for proteomic research.

TL;DR: It is believed that most of the existing technology is capable of displaying many more proteins than is currently achievable by integrating existing and new techniques to prefractionate samples prior to 2‐DE display or analysis.
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Characterization of the Role of the Rab GTPase-activating Protein AS160 in Insulin-regulated GLUT4 Trafficking

TL;DR: Findings support an important role for AS160 in the insulin regulated trafficking of GLUT4, which is mediated by the cytosolic tail of insulin-regulated aminopeptidase which interacted both in vitro and in vivo with AS160.
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A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton.

TL;DR: By binding both CD2AP and the Arp2/3 complex, cortactin links receptor endocytosis to actin polymerization, which may facilitate the trafficking of internalized growth factor receptors.