V
Vanessa A. York
Researcher at University of California, San Francisco
Publications - 28
Citations - 2204
Vanessa A. York is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Interleukin 21 & Cytotoxic T cell. The author has an hindex of 16, co-authored 28 publications receiving 1842 citations. Previous affiliations of Vanessa A. York include University of California.
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Journal ArticleDOI
Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection
Sandra López-Vergès,Jeffrey M. Milush,Brian S. Schwartz,Marcelo J. Pando,Jessica Jarjoura,Vanessa A. York,Jeffrey P. Houchins,Steve Miller,Sang-Mo Kang,Phillip J. Norris,Douglas F. Nixon,Lewis L. Lanier +11 more
TL;DR: The preferential expansion of a unique subset of NK cells coexpressing the activating CD94–NKG2C receptor and CD57 in CMV+ donors is demonstrated and it is proposed that CD57 might provide a marker of “memory” NK cells that have been expanded in response to infection.
Journal ArticleDOI
CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset
Sandra López-Vergès,Jeffrey M. Milush,Suchitra Pandey,Vanessa A. York,Janice Arakawa-Hoyt,Hanspeter Pircher,Phillip J. Norris,Phillip J. Norris,Douglas F. Nixon,Lewis L. Lanier +9 more
TL;DR: A combination of a mature phenotype, a higher cytotoxic capacity, aHigher sensitivity to stimulation via CD16, with a decreased responsiveness to cytokines, and a decreased capacity to proliferate suggest that CD57(+) NK cells are highly mature and might be terminally differentiated.
Journal ArticleDOI
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.
Jeffrey D. Whitman,Joseph Hiatt,Cody T. Mowery,Brian R. Shy,Ruby Yu,Tori N. Yamamoto,Ujjwal Rathore,Gregory M. Goldgof,Caroline Whitty,Jonathan M. Woo,Jonathan M. Woo,Antonia E. Gallman,Tyler E. Miller,Andrew G. Levine,David N. Nguyen,David N. Nguyen,Sagar P. Bapat,Joanna Balcerek,Sophia A. Bylsma,Ana M. Lyons,Stacy Li,Allison W. Wong,Eva M. Gillis-Buck,Zachary Steinhart,Youjin Lee,Ryan Apathy,Ryan Apathy,Mitchell J. Lipke,Jennifer A Smith,Tina Zheng,Ian C. Boothby,Erin Isaza,Jackie Chan,Dante D. Acenas,Jinwoo Lee,Trisha A. Macrae,Than S. Kyaw,David Wu,Dianna Ng,Wei Gu,Vanessa A. York,Haig A. Eskandarian,Perri C. Callaway,Perri C. Callaway,Lakshmi Warrier,Mary E. Moreno,Justine Levan,Leonel Torres,Lila A. Farrington,Rita P. Loudermilk,Kanishka Koshal,Kelsey C. Zorn,Wilfredo F. Garcia-Beltran,Diane Yang,Michael G Astudillo,Bradley E. Bernstein,Jeffrey A. Gelfand,Edward T. Ryan,Richelle C. Charles,A. John Iafrate,Jochen K. Lennerz,Steve Miller,Charles Y. Chiu,Susan L. Stramer,Michael R. Wilson,Aashish Manglik,Chun Jimmie Ye,Nevan J. Krogan,Nevan J. Krogan,Mark S. Anderson,Jason G. Cyster,Joel D. Ernst,Alan H.B. Wu,Kara L. Lynch,Caryn Bern,Patrick D. Hsu,Alexander Marson +76 more
TL;DR: A head-to-head evaluation of ten point-of-care-style lateral flow assays and two laboratory-based enzyme-linked immunosorbent assays to detect anti-SARS-CoV-2 IgM and IgG antibodies in 5-d time intervals from symptom onset underline the importance of seropositivity threshold determination and reader training for reliable LFA deployment.
Journal ArticleDOI
CD56negCD16+NK cells are activated mature NK cells with impaired effector function during HIV-1 infection
Jeffrey M. Milush,Sandra López-Vergès,Vanessa A. York,Steven G. Deeks,Jeffrey N. Martin,Frederick Hecht,Lewis L. Lanier,Douglas F. Nixon,Douglas F. Nixon +8 more
TL;DR: It is found that CD3negCD56negCD16+ cells are a heterogeneous population comprised of CD7+ NK cells and CD7neg non-classical myeloid cells that may have recently engaged target cells.
Journal ArticleDOI
Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4
Jeffrey M. Milush,Brian Long,Jennifer E. Snyder-Cappione,Amedeo Cappione,Vanessa A. York,Lishomwa C. Ndhlovu,Lewis L. Lanier,Jakob Michaëlsson,Douglas F. Nixon +8 more
TL;DR: Novel subsets of peripheral blood CD3/14/19(neg) NK cells and monocyte/dendritic cell (DC)-like cells were identified on the basis of CD7 and CD4 expression to improve the ability to study the intricacies of NK-cell subset phenotypes and functions in vivo.