V
Vidalba Rocher-Ros
Researcher at Queen Mary University of London
Publications - 7
Citations - 732
Vidalba Rocher-Ros is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Inflammation & Synovitis. The author has an hindex of 4, co-authored 6 publications receiving 476 citations.
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Journal ArticleDOI
Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions.
Robert Haas,Joanne Smith,Vidalba Rocher-Ros,Suchita Nadkarni,Trinidad Montero-Melendez,Fulvio D'Acquisto,Elliot James Bland,Michele Bombardieri,Costantino Pitzalis,Mauro Perretti,Federica M. Marelli-Berg,Claudio Mauro +11 more
TL;DR: A novel role of lactate is established in control of proinflammatory T cell motility and effector functions, which provides a potential molecular mechanism for T cell entrapment and functional changes in inflammatory sites that drive chronic inflammation and offer targeted therapeutic interventions for the treatment of chronic inflammatory disorders.
Journal ArticleDOI
Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
Myles Lewis,Michael R. Barnes,Michael R. Barnes,K. Blighe,Katriona Goldmann,Sharmila Rana,Jason A. Hackney,Nandhini Ramamoorthi,Christopher R. John,David Watson,David Watson,David Watson,Sarah K. Kummerfeld,Rebecca Hands,Sudeh Riahi,Vidalba Rocher-Ros,Felice Rivellese,Frances Humby,Stephen Kelly,Michele Bombardieri,Nora Ng,M DiCicco,Désirée van der Heijde,Robert Landewé,Annette H M van der Helm-van Mil,Alberto Cauli,Iain B. McInnes,Christopher D. Buckley,Christopher D. Buckley,Ernest Choy,Peter C. Taylor,Michael J. Townsend,Costantino Pitzalis +32 more
TL;DR: In this paper, a comprehensive RNA sequencing analysis of the molecular pathways that drive early RA progression in the disease tissue (synovium), comparing matched peripheral blood RNA-seq in a large cohort of early treatment-naive patients, namely, the Pathobiology of Early Arthritis Cohort (PEAC).
Journal ArticleDOI
Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis
Gareth W. Jones,Michele Bombardieri,Claire J. Greenhill,Louise McLeod,Alessandra Nerviani,Vidalba Rocher-Ros,Anna Cardus,Anwen Sian Williams,C. Pitzalis,Brendan J. Jenkins,Simon Arnett Jones +10 more
TL;DR: Increased numbers of podoplanin-expressing Th17 cells in the absence of IL-27R signaling may be involved in driving ELS formation.
Journal ArticleDOI
Treatment-resistant synovitis and radiographic progression are increased in elderly-onset rheumatoid arthritis patients: findings from a prospective observational longitudinal early arthritis cohort study.
Vasco C. Romão,Frances Humby,Stephen Kelly,Maria Di Cicco,Arti Mahto,Ilias Lazarou,Rebecca Hands,Vidalba Rocher-Ros,Désirée van der Heijde,João Eurico Fonseca,Costantino Pitzalis +10 more
TL;DR: Early EORA presents differently and has a worse overall prognosis than YORA, with poorer clinical, histological, ultrasonographic and radiographic outcomes.
Journal Article
Ultrasound-guided synovial biopsy of the wrist does not alter subsequent clinical or ultrasound disease activity assessments: a prospective study for incorporation of imaging in clinical trials.
Ilias Lazarou,Stephen Kelly,Frances Humby,Maria Di Cicco,Lu Zou,Vidalba Rocher-Ros,Rebecca Hands,Nora Ng,Arti Mahto,Costantino Pitzalis +9 more
TL;DR: In this population of rheumatoid arthritis patients, UGSB of the wrist did not significantly alter subsequent clinical or US assessments, indicating that a wrist joint, which has undergone U GSB, may be incorporated into an US dataset or clinical outcome assessment tools, such as the DAS-28, without prejudice.