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Weijuan Huang
Researcher at Chinese Center for Disease Control and Prevention
Publications - 49
Citations - 1558
Weijuan Huang is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Virus & Neuraminidase. The author has an hindex of 17, co-authored 39 publications receiving 1278 citations. Previous affiliations of Weijuan Huang include National Health and Family Planning Commission & Centers for Disease Control and Prevention.
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Journal ArticleDOI
Biological features of novel avian influenza A (H7N9) virus
Jiangfang Zhou,Dayan Wang,Rongbao Gao,Baihui Zhao,Jingdong Song,Xian Qi,Yanjun Zhang,Yonglin Shi,Lei Yang,Wenfei Zhu,Tian Bai,Kun Qin,Yu Lan,Shumei Zou,Junfeng Guo,Jie Dong,Libo Dong,Ye Zhang,Hejiang Wei,Xiaodan Li,Jian Lu,Liqi Liu,Xiang Zhao,Xiyan Li,Weijuan Huang,Le-ying Wen,Hong Bo,Li Xin,Y. Chen,Cuilin Xu,Yuquan Pei,Yue Yang,Xiaodong Zhang,Shiwen Wang,Zijian Feng,Jun Han,Weizhong Yang,George F. Gao,Guizhen Wu,Dexin Li,Yu Wang,Yuelong Shu +41 more
TL;DR: It is shown that the emerging H7N9 avian influenza virus poses a potentially high risk to humans, and current seasonal vaccination could not provide protection.
Journal ArticleDOI
Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors and status of novel antivirals, 2016–2017
Angie Lackenby,Terry G. Besselaar,Rod S. Daniels,Alicia M. Fry,Vicki Gregory,Larisa V. Gubareva,Weijuan Huang,Aeron C. Hurt,Sook-Kwan Leang,Raphael T.C. Lee,Janice Lo,Lori Lollis,Sebastian Maurer-Stroh,Takato Odagiri,Dmitriy Pereyaslov,Emi Takashita,Dayan Wang,Wenqing Zhang,Adam Meijer +18 more
TL;DR: This 2016/17 analysis demonstrates that neuraminidase inhibitors remain suitable for treatment and prophylaxis of influenza virus infections, but continued monitoring is important.
Journal ArticleDOI
Genesis and Spread of Newly Emerged Highly Pathogenic H7N9 Avian Viruses in Mainland China.
Lei Yang,Wenfei Zhu,Xiyan Li,Minmei Chen,Jie Wu,Pengbo Yu,Shun-Xiang Qi,Yiwei Huang,Weixian Shi,Jie Dong,Xiang Zhao,Weijuan Huang,Zi Li,Xiaoxu Zeng,Hong Bo,Tao Chen,Wenbing Chen,Jia Liu,Ye Zhang,Zhenli Liang,Wei Shi,Yuelong Shu,Yuelong Shu,Dayan Wang +23 more
TL;DR: This study comprehensively analyzed the sequences of HPAI H7N9 viruses from 28 human and 21 environmental samples covering eight provinces in China that were taken from November 2016 to June 2017 and showed that the ancestor virus of the HPAi H7n9 viruses originated in the Yangtze River Delta region.
Journal ArticleDOI
Biological characterisation of the emerged highly pathogenic avian influenza (HPAI) A(H7N9) viruses in humans, in mainland China, 2016 to 2017
Wenfei Zhu,Jianfang Zhou,Zi Li,Lei Yang,Xiyan Li,Weijuan Huang,Sumei Zou,Wenbing Chen,Hejiang Wei,Jing Tang,Liqi Liu,Jie Dong,Dayan Wang,Yuelong Shu +13 more
TL;DR: The insertion of four amino acids at the haemagglutinin cleavage site enabled trypsin-independent infectivity of this virus and the neuraminidase substitution R292K conferred a multidrug resistance phenotype.
Journal ArticleDOI
mapping of H3n2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation
Xiangjun Du,Libo Dong,Yu Lan,Yousong Peng,Aiping Wu,Ye Zhang,Weijuan Huang,Dayan Wang,Min Wang,Yuan-ji Guo,Yuelong Shu,Taijiao Jiang +11 more
TL;DR: This work develops a computational method, denoted as PREDAC, to predict antigenic clusters of influenza A (H3N2) viruses with high accuracy from viral HA sequences and demonstrates that the coupling of large-scale HA sequencing withPREDAC can significantly improve vaccine strain recommendation for China.