W
Werner Hacke
Researcher at Heidelberg University
Publications - 688
Citations - 93115
Werner Hacke is an academic researcher from Heidelberg University. The author has contributed to research in topics: Stroke & Thrombolysis. The author has an hindex of 123, co-authored 656 publications receiving 84593 citations. Previous affiliations of Werner Hacke include University Hospital Heidelberg & Steklov Mathematical Institute.
Papers
More filters
Journal ArticleDOI
Effect of Intravenous Thrombolysis on MRI Parameters and Functional Outcome in Acute Stroke <6 Hours
J. Röther,Peter D. Schellinger,Achim Gass,Mario Siebler,Arno Villringer,Jochen B. Fiebach,Jens Fiehler,Olav Jansen,Thomas Kucinski,Volker Schoder,Kristina Szabo,Gerhard J. Jungehulsing,M. Hennerici,H. Zeumer,K. Sartor,Cornelius Weiller,Werner Hacke +16 more
TL;DR: Multiparametric MRI delineates tissue at risk of infarction in AIS patients, which may be helpful for the selection of patients for tPA therapy, and delivers the rationale for a randomized, MR-based tPA trial.
Journal ArticleDOI
Decompressive surgery in space-occupying hemispheric infarction: results of an open, prospective trial.
Klaus Rieke,Stefan Schwab,Derk W. Krieger,Rüdiger von Kummer,Alfred Aschoff,Volker Schuchardt,Werner Hacke +6 more
TL;DR: Hemicraniotomy may improve survival in massive hemispheric stroke victims, decreasing mortality rates to < 35%, although some patients seem to benefit significantly.
Journal ArticleDOI
Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats.
TL;DR: Results show that pretreatment with intraventricular BDNF reduces infarct size after focal cerebral ischemia in rats and support the hypothesis of a neuroprotective role for BDNF in stoke.
Journal ArticleDOI
World Stroke Organization (WSO): Global Stroke Fact Sheet 2022
Valery L. Feigin,Michael Brainin,Bo Norrving,Sheila Cristina Ouriques Martins,Ralph L. Sacco,Werner Hacke,Marc Fisher,Jeyaraj D Pandian,Patrice Lindsay +8 more
TL;DR: This World Stroke Organisation (WSO) Global Stroke Fact Sheet 2022 provides the most updated information that can be used to inform communication with all internal and external stakeholders.
Journal ArticleDOI
Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial
Erich Bluhmki,Ángel Chamorro,Antoni Dávalos,Thomas Machnig,C. Sauce,Nils Wahlgren,Joanna M. Wardlaw,Werner Hacke +7 more
TL;DR: The results support the use of alteplase up to 4.5 h after the onset of stroke symptoms across a broad range of subgroups of patients who meet the requirements of the European product label but miss the approved treatment window of 0-3 h.