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Werner Hacke
Researcher at Heidelberg University
Publications - 688
Citations - 93115
Werner Hacke is an academic researcher from Heidelberg University. The author has contributed to research in topics: Stroke & Thrombolysis. The author has an hindex of 123, co-authored 656 publications receiving 84593 citations. Previous affiliations of Werner Hacke include University Hospital Heidelberg & Steklov Mathematical Institute.
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Patient outcomes in historical comparators compared with randomised-controlled trials
TL;DR: The beneficial effects of decompressive hemicraniectomy on survival were not confirmed using a historical comparator dataset, and patients identified from Virtual International Stroke Trials Archive may not have been truly representative of patients with malignant middle cerebral artery infarction.
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Googling Stroke ASPECTS to determine disability: Exploratory analysis from vista-acute collaboration
Richard Beare,Richard Beare,Jian Chen,Jian Chen,Thanh G. Phan,Kennedy R. Lees,Myzoon Ali,Andrei V. Alexandrov,Philip M.W. Bath,Erich Bluhmki,N. M. Bornstein,L. Claesson,Stephen M. Davis,Geoffrey A. Donnan,H. C. Diener,Marc Fisher,Myron D. Ginsberg,Barbara A. Gregson,James C. Grotta,Werner Hacke,M.G. Hennerici,Marc Hommel,Markku Kaste,P. Lyden,John R. Marler,K. W. Muir,Ralph L. Sacco,A. Shuaib,P. Teal,N Wahlgren,Steven Warach,C. Weimar +31 more
TL;DR: The PageRank method reveals complex interaction among ASPECTS regions with respects to disability and may help to understand the infarcted brain network involved in stroke disability.
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Thrombolysis in acute cerebrovascular disease: indications and limitations.
TL;DR: Large-scale trials have shown that thrombolytic therapy reduces mortality and preserves left ventricular function in patients with acute myocardial infarction (AMI), and Streptokinase and recombinant tissue plasminogen activator (rt-PA) are the agents that have been the most widely investigated in stroke studies.
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Hyperbaric oxygen therapy (HBO) after acute focal cerebral ischemia
TL;DR: This review focuses on the clinical perspective of HBO therapy and summarizes both the clinical and experimental data availabe on HBO therapy following ischemic stroke.
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Commentary on a GWAS: HDAC9 and the risk for ischaemic stroke
TL;DR: The findings suggest that well-recognized clinical stroke subtypes correspond to distinct aetiological entities, but the molecular pathways that are affected by the identified genetic variants are not yet pinpointed, and the observed associations apply only for some, but not all victims of a specific stroke aetiology.