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Werner Hacke
Researcher at Heidelberg University
Publications - 688
Citations - 93115
Werner Hacke is an academic researcher from Heidelberg University. The author has contributed to research in topics: Stroke & Thrombolysis. The author has an hindex of 123, co-authored 656 publications receiving 84593 citations. Previous affiliations of Werner Hacke include University Hospital Heidelberg & Steklov Mathematical Institute.
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Journal ArticleDOI
Dichotomized Efficacy End Points and Global End-Point Analysis Applied to the ECASS Intention-to-Treat Data Set Post Hoc Analysis of ECASS I
Werner Hacke,Erich Bluhmki,Thorsten Steiner,Turgut Tatlisumak,Marie-Hélène Mahagne,Marisa-Luisa Sacchetti,Dieter Meier +6 more
TL;DR: Using the global end-point analysis, ECASS is positive in the intention-to-treat analysis, which may indicate that the time window for thrombolysis may be as long as 6 hours.
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Cost-Effectiveness of Solitaire Stent Retriever Thrombectomy for Acute Ischemic Stroke: Results From the SWIFT-PRIME Trial (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke).
Theresa I. Shireman,Kaijun Wang,Jeffrey L. Saver,Mayank Goyal,Alain Bonafe,Hans-Christoph Diener,Elad I. Levy,Vitor Mendes Pereira,Gregory W. Albers,Christophe Cognard,Werner Hacke,Olav Jansen,Tudor G Jovin,Heinrich Mattle,Raul G Nogueira,Adnan H. Siddiqui,Dileep R. Yavagal,Thomas Devlin,Demetrius K. Lopes,Vivek Y. Reddy,Richard du Mesnil de Rochemont,Reza Jahan,Katherine Vilain,John A. House,Jin-Moo Lee,David Cohen +25 more
TL;DR: Among patients with acute ischemic stroke enrolled in the SWIFT-PRIME trial, SST increased initial treatment costs, but was projected to improve quality-adjusted life-expectancy and reduce healthcare costs over a lifetime horizon compared with tPA.
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Priorities to reduce the burden of stroke in Latin American countries
Sheila Cristina Ouriques Martins,Claudio Sacks,Werner Hacke,Michael Brainin,Francisco de Assis Figueiredo,Octavio M. Pontes-Neto,Pablo M Lavados Germain,Pablo M Lavados Germain,Pablo M Lavados Germain,Maria F Marinho,Arnold Hoppe Wiegering,Arnold Hoppe Wiegering,Diana Vaca McGhie,Salvador Cruz-Flores,Sebastián F. Ameriso,Walter M Camargo Villareal,Juan Carlos Durán,José E Fogolin Passos,Raul G Nogueira,João José Freitas de Carvalho,Gisele Sampaio Silva,Carla H.C. Moro,Jamary Oliveira-Filho,Rubens José Gagliardi,Eduardo D Gomes de Sousa,Felipe Fagundes Soares,Katia de Pinho Campos,Paulo F Piza Teixeira,Ivete Pillo Gonçalves,Irving R Santos Carquin,Mário Muñoz Collazos,Germán Enrique Pérez Romero,Javier I Maldonado Figueredo,Miguel A Barboza,Miguel Á Celis López,Fernando Góngora-Rivera,Carlos Cantú-Brito,Nelson Novarro-Escudero,Miguel Á Velázquez Blanco,Carlos A Arbo Oze de Morvil,Gloria Meza Rojas,Alan Flores,Jorge Arturo Hancco-Saavedra,Vivian Pérez Jimenez,Carlos Abanto Argomedo,Liliana Rodriguez Kadota,Roberto Crosa,Daissy L Mora Cuervo,Ana C de Souza,Leonardo A Carbonera,Tony F Álvarez Guzmán,Nelson Maldonado,Norberto L. Cabral,Craig S. Anderson,Patrice Lindsay,Anselm Hennis,Valery L. Feigin +56 more
TL;DR: The meeting culminated with the adoption of the special Gramado Declaration, signed by all Ministerial officials who attended the meeting and an opportunity now exists to translate this Declaration into an action plan to reduce the burden of stroke.
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Induction of FOS and JUN proteins after focal ischemia in the rat: differential effect of the N-methyl-D-aspartate receptor antagonist MK-801.
TL;DR: The rapid IEG induction in the entire ipsilateral sensorimotor and limbic structure-associated cortices after photochemically induced infarction most likely reflects spreading depression caused by ischemia and mediated by NMDA receptors.
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