Werner Hacke

TL;DR: The data are consistent with, but do not prove the hypothesis that early addition of clopidogrel to acetylsalicylic acid in patients with transient ischaemic attack and ischaemia stroke of arterial origin may be more effective and acceptably safe compared with acetyl salicylic Acid alone.

TL;DR: Surgical treatment still remains the gold standard for treatment of patients with symptomatic carotid artery stenosis, who do not have an increased surgical risk in large clinical trials when short-term stroke and death rates are taken into account.

TL;DR: The results provide the first evidence that serum from CIM patients affects membrane excitability and the excitation-contraction coupling process at the level of the sarcoplasmic reticulum Ca2+ release of mammalian muscle fibres and show that even control serum fractions ‘per se’ alter the response to important physiological membrane and contractility parameters compared with physiological saline.

TL;DR: Laminin-5 and MMP presence relate directly to the degree of postischemic injury and hypothermia reduces the conversion from the I(r) to ischemic core and the degrees of BBB as well as MMP abundance.