Werner Hacke

TL;DR: No relationship was seen between CYP2C19 status and ischaemic outcomes in stable patients treated with clopidogrel, suggesting less anti-platelet response and a potential link with reduced bleeding complications.

TL;DR: The European Stroke Initiative (EUSI) has authorized the writing committee of the EUSI to create recommendations for stroke management covering all areas of stroke treatment, which are called recommendations rather than guidelines in order to underline the large amount of individual decision making.

TL;DR: There were several potential reasons for the low recruitment rates into SPACE-2, including the ability for referring doctors to refer their patients directly for CEA or CAS outwith the trial, an inability to convince patients (who had come "mentally prepared" that an intervention was necessary) to accept BMT, and other economic constraints.

TL;DR: Stroke is a major cause of death and disability in industrialized countries, but stroke awareness is still generally poor and treatment often ill-defined.

TL;DR: It appears unjustified to limit thrombolytic therapy to 3 hours, and better methods for patient selection are required; in particular, newer MRI techniques, such as diffusion- and perfusion-weighted imaging, can play a key role.