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William Fenical
Researcher at University of California, San Diego
Publications - 591
Citations - 36313
William Fenical is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Streptomyces & Laurencia. The author has an hindex of 97, co-authored 578 publications receiving 34003 citations. Previous affiliations of William Fenical include University of North Carolina at Chapel Hill & University of Concepción.
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Journal ArticleDOI
Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.
Feling Robert H R,Greg O. Buchanan,Tracy J. Mincer,Christopher A. Kauffman,Paul R. Jensen,William Fenical +5 more
TL;DR: The ocean is an overlooked habitat from which to isolate important microorganisms, and the rate of discovery of new biologically active compounds from common soil actino-mycetes has been falling.
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Developing a new resource for drug discovery: marine actinomycete bacteria
William Fenical,Paul R. Jensen +1 more
TL;DR: The continued development of improved cultivation methods and technologies for accessing deep-sea environments promises to provide access to this significant new source of chemical diversity.
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Marine Plant-Herbivore Interactions: The Ecology of Chemical Defense
Mark E. Hay,William Fenical +1 more
TL;DR: Although numerous seaweed characteristics can deter some herbivores, the effects of morphology and chemistry have been studied most thoroughly and these types of seaweeds may be considered herbivore tolerant.
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Widespread and persistent populations of a major new marine actinomycete taxon in ocean sediments.
TL;DR: This study presents the first evidence for the existence of widespread populations of obligate marine actinomycetes from ocean sediments, and suggests novelty at the genus level.
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Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica
Daniel W. Udwary,Lisa Zeigler,Ratnakar N. Asolkar,Vasanth R. Singan,Alla Lapidus,William Fenical,Paul R. Jensen,Bradley S. Moore +7 more
TL;DR: The S. tropica CNB-440 circular genome of Salinispora species was sequenced and analyzed in this paper, which revealed the powerful interplay between genomic analysis and traditional natural product isolation studies.