Keith James

TL;DR: The cause of bladder cancer is unknown, but the disease has been strongly associated with exposure to certain aromatic chemicals, notably aniline dyes and benzidine compounds.

TL;DR: The development of human monoclonal antibody technology has been a slow, laborious and often unrewarding exercise, but in spite of the many problems encountered to date work has continued unabated, sustained by the widely held belief that this technology would result in improved diagnostics and therapeutics and would increase the understanding of human biology.

TL;DR: The interaction between α 2 -macroglobulin and a number of cytokines has recently come under scrutiny, revealing a new and potentially important mechanism for the modulation of cytokine activity, while in the following paper a modulatory role for anti-cytokine antibodies is considered.

TL;DR: In this article , the authors demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273.529.

TL;DR: The main findings on immunohistochemical analysis were the universal induction of MHC Class II antigens by urothelial cells which was statistically significant up to 6 months after completion of therapy, coupled with a T cell dominated cystitis.