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Wing-Kin Sung
Researcher at National University of Singapore
Publications - 335
Citations - 28128
Wing-Kin Sung is an academic researcher from National University of Singapore. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 64, co-authored 327 publications receiving 26116 citations. Previous affiliations of Wing-Kin Sung include University of Hong Kong & Yale University.
Papers
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Journal Article
Rooted maximum agreement supertrees
TL;DR: The maximum agreement supertree problem (MASP) is proved to be NP-hard for any fixed k ≥ 3 when D is unrestricted, and also NP- hard forAny fixed D ≥ 2 when k is unrestricted even if each input tree is required to contain at most three leaves.
Book ChapterDOI
Inference of spatial organizations of chromosomes using semi-definite embedding approach and hi-c data
TL;DR: A deterministic method called ChromSDE is presented, which applies semi-definite programming techniques to find the best structure fitting the observed data and uses golden section search to finding the correct parameter for converting the contact frequency to spatial distance and is shown to be much more accurate and robust than existing methods.
Journal ArticleDOI
Succinct data structures for Searchable Partial Sums with optimal worst-case performance
TL;DR: This paper shows that even for k = O ( lg lg n), the authors can index A succinctly such that both query and update operations can be supported using the same time complexities, and the time for update becomes the worst-case time.
Journal ArticleDOI
HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer.
Canhui Cao,Ping Hong,Xingyu Huang,Da Lin,Gang Cao,Liming Wang,Bei Feng,Ping Wu,Hui Shen,Qian Xu,Ci Ren,Yifan Meng,Wenhua Zhi,Ruidi Yu,Juncheng Wei,Wencheng Ding,Xun Tian,Qinghua Zhang,Wei Li,Qinglei Gao,Gang Chen,Kezhen Li,Wing-Kin Sung,Zheng Hu,Hui Wang,Guoliang Li,Peng Wu +26 more
TL;DR: In insight into the 3D structural mechanism underlying HPV integration in cervical carcinogenesis, it is found that HPV-CCDC106 integration altered local chromosome architecture and hijacked an enhancer via 3D genome structure remodeling.
Book ChapterDOI
Constructing a smallest refining galled phylogenetic network
TL;DR: Two new efficient algorithms for inferring a phylogenetic network from a set of gene trees of arbitrary degrees named RGNet and RGNet are presented and it is shown that these methods outperform the other existing methods neighbor-joining, NeighborNet, and SpNet.