Wing-Kin Sung

TL;DR: It is confirmed that large insert libraries allow for the identification of SVs within repetitive sequences, which cannot be spanned by short inserts, and it is shown how it can be used in a fusion-point-guided-concatenation algorithm to study focally amplified regions in cancer.

TL;DR: This work has developed and field-tested a resequencing kit that is capable of interrogating all eight segments of the 2009 influenza A(H1N1) virus genome and its variants, with added focus on critical regions such as drug-binding sites, structural components and mutation hotspots.

TL;DR: A stepwise topological transformation of genome is introduced from 1‐dimension (1D, linear) to 2‐ dimension (2D, networks) to 3‐dimensional (3D, architecture) to discuss how such transformations could advance the understanding of genome biology.

TL;DR: Transcriptome sequencing of H CC patients reveals key cancer molecules and clinically relevant pathways deregulated/mutated in HCC patients and suggests that while HBV may integrate randomly during chronic infection, selective expression of functional chimeric transcripts likely occur during the process of tumorigenesis.

TL;DR: New deterministic algorithms for constructing consensus trees that are faster than all the previously known ones are presented, and are optimal since the input size is Ω(nk).