Wing-Kin Sung

TL;DR: Of the 29 MDSR genes targeted by RNA interference, three showed a requirement for cell-cycle entry upon serum stimulation and 11 for long-term proliferation and/or survival, Hence, proper coordination of key regulatory and biosynthetic pathways following mitogenic stimulation relies upon the concerted regulation of multiple Myc-dependent genes.

TL;DR: The above time-and-space barrier under the unit-cost word RAM is broken, and for the special case where $\log|\Sigma|=O((\log\log n)^{1-\epsilon})$, the authors can speed up their suffix array construction algorithm to the optimal $O(n)$.

TL;DR: The first succinct tree representation supporting every one of the fundamental operations previously proposed for BP or DFUDS along with some new operations in constant time is given, its size surpasses the information-theoretic lower bound and matches the entropy of the tree based on the distribution of node degrees.

TL;DR: It is proved that the problem of determining whether a given set $\T$ of rooted triplets can be merged without conflicts into a galled phylogenetic network and, if so, constructing such a network is NP-hard if extended to nondense inputs.

TL;DR: Detailed procedures of the ChIA-PET methodology are described, unraveling transcription-associated chromatin contacts in a model human cell line, providing a global and unbiased interrogation of higher-order chromatin structures associated with specific protein factors.