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Wing-Kin Sung
Researcher at National University of Singapore
Publications - 335
Citations - 28128
Wing-Kin Sung is an academic researcher from National University of Singapore. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 64, co-authored 327 publications receiving 26116 citations. Previous affiliations of Wing-Kin Sung include University of Hong Kong & Yale University.
Papers
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Journal ArticleDOI
Reconstructing Recombination Network from Sequence Data: The Small Parsimony Problem
TL;DR: The small parsimony problem is studied for reconstructing recombination networks from sequence data and is polynomial-time solvable for phylogenetic trees.
Journal ArticleDOI
SurVirus: a repeat-aware virus integration caller.
Ramesh Rajaby,Yi Zhou,Yifan Meng,Xi Zeng,Guoliang Li,Peng Wu,Wing-Kin Sung,Wing-Kin Sung,Wing-Kin Sung +8 more
TL;DR: Wang et al. as mentioned in this paper proposed SurVirus, an improved virus integration caller that corrects the alignment of reads which are crucial for the discovery of integrations, and used publicly available datasets to show that existing methods predict hundreds of thousands of false positives.
Journal ArticleDOI
The Integrator Complex Prevents Dedifferentiation of Intermediate Neural Progenitors back into Neural Stem Cells
Yingjie Zhang,Chwee Tat Koe,Ye Sing Tan,Joses Ho,Patrick Tan,Fengwei Yu,Wing-Kin Sung,Hongyan Wang +7 more
TL;DR: It is demonstrated that the Drosophila Integrator complex prevents dedifferentiation of intermediate neural progenitors (INPs) during neural stem cell (neuroblast) lineage development by regulating a key transcription factor Erm that also suppresses INP dedifferentiated.
Journal ArticleDOI
Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes.
Kuo Ping Chiu,Pramila N. Ariyaratne,Han Xu,Adrian Tan,Patrick Ng,Edison T. Liu,Yijun Ruan,Chia-Lin Wei,Wing-Kin Sung,Wing-Kin Sung +9 more
TL;DR: The highly correlated results unmistakably point to a systematic downregulation of mitochondrial activities, which is hypothesize aims to downgrade the mitochondria-mediated apoptosis and the dependency of cancer cells on angiogenesis.
Book ChapterDOI
Local gapped subforest alignment and its application in finding RNA structural motifs
TL;DR: It is proved that a special case of the local gapped subforest alignment problem is equivalent to a problem known in the literature as the local sequence-structure alignment problem (lssa) and the main algorithm is modified to obtain a much faster algorithm for lssa than the one previously proposed.