X
Xiang Zhou
Researcher at University of Michigan
Publications - 172
Citations - 20187
Xiang Zhou is an academic researcher from University of Michigan. The author has contributed to research in topics: Medicine & Genome-wide association study. The author has an hindex of 33, co-authored 133 publications receiving 16025 citations. Previous affiliations of Xiang Zhou include Duke University & University of Chicago.
Papers
More filters
Journal ArticleDOI
Constructing Sub 10 nm Scale Interfused TiO2/SiOx Bicontinuous Hybrid with Mutual-Stabilizing Effect for Lithium Storage.
TL;DR: In this article , a sub 10 nm scale interfused TiO2/SiOx hybrid with a bicontinuous structure was constructed, in which bridged TiO 2 nanoparticles (over 80 wt %) are densely packed within a wormlike SiOx network, through the simple oxidation of MAX Ti3SiC2 ceramic.
Journal ArticleDOI
MCC-SP: a powerful integration method for identification of causal pathways from genetic variants to complex disease
Yuchen Zhu,Jiadong Ji,Weiqiang Lin,Mingzhuo Li,Lu Liu,Huanhuan Zhu,Fuzhong Xue,Xiujun Li,Xiang Zhou,Zhongshang Yuan +9 more
TL;DR: A method to measure the between-node connection strength and rank the effects of chain-type pathways from genetic variant to disease, which can provide statistical evidence to give the priority of some pathways for potential drug development in a cost-effective manner is introduced.
Journal ArticleDOI
PGS-server: accuracy, robustness and transferability of polygenic score methods for biobank scale studies
Sheng Yang,Xiang Zhou +1 more
TL;DR: A comprehensive comparison study on 12 different PGS methods is performed, and a simple aggregation strategy is presented that combines multiple PGS from different methods to take advantage of their distinct benefits to achieve stable and superior prediction performance.
Journal ArticleDOI
Screening for gene–environment (G×E) interaction using omics data from exposed individuals: an application to gene-arsenic interaction
Maria Argos,Lin Tong,Shantanu Roy,Shantanu Roy,Mekala Sabarinathan,Alauddin Ahmed,Md. Tariqul Islam,Tariqul Islam,Muhammad Rakibuz-Zaman,Golam Sarwar,Hasan Shahriar,Mahfuzar Rahman,Md. Yunus,Joseph H. Graziano,Farzana Jasmine,Muhammad G. Kibriya,Xiang Zhou,Habibul Ahsan,Brandon L. Pierce +18 more
TL;DR: A novel two-step approach using omics data to conduct genome-wide searches for gene-arsenic interactions that will enhance the understanding of disease etiology and the ability to develop interventions targeted at susceptible sub-populations is described.
Journal ArticleDOI
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)
Farah Ammous,Wei Zhao,Lisha Lin,Scott M. Ratliff,Thomas H. Mosley,Lawrence F. Bielak,Xiang Zhou,Patricia A. Peyser,Sharon L.R. Kardia,Jennifer A. Smith +9 more
TL;DR: In this paper , the association between DNA methylation and atherosclerosis at multiple vascular sites in a sample of African-Americans was investigated using linear mixed models, and the association was shown to be relatively stable over 5 years, with the highest correlation coefficients observed for MRScarotid and GrimAge acceleration.