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Xiang Zhou
Researcher at University of Michigan
Publications - 172
Citations - 20187
Xiang Zhou is an academic researcher from University of Michigan. The author has contributed to research in topics: Medicine & Genome-wide association study. The author has an hindex of 33, co-authored 133 publications receiving 16025 citations. Previous affiliations of Xiang Zhou include Duke University & University of Chicago.
Papers
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Journal ArticleDOI
Methods for large‐scale single mediator hypothesis testing: Possible choices and comparisons
Jiacong Du,Xiang Zhou,Dylan Clark-Boucher,Wei Hao,Yongmei Liu,Jennifer A. Smith,Bhramar Mukherjee +6 more
TL;DR: The class of methods which uses a mixture reference distribution could best maintain the false positive rates at the nominal level under the null hypothesis and had the greatest true positive rates under the alternative hypothesis.
Peer ReviewDOI
Author response: A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics
Irene Gallego Romero,Bryan J Pavlovic,Irene Hernando-Herraez,Xiang Zhou,Michelle C Ward,Nicholas E. Banovich,Courtney L. Kagan,Jonathan E. Burnett,Constance H. Huang,Amy Mitrano,Claudia Chavarria,Inbar Friedrich Ben-Nun,Yingchun Li,Karen Sabatini,Karen Sabatini,Trevor R. Leonardo,Trevor R. Leonardo,Mana M. Parast,Tomas Marques-Bonet,Louise C. Laurent,Jeanne F. Loring,Yoav Gilad +21 more
Posted ContentDOI
Single cell analysis of the effects of developmental lead (Pb) exposure on the hippocampus
Kelly M. Bakulski,John F. Dou,Robert C. Thompson,Christopher Lee,Lauren Y. M. Middleton,Bambarendage P. U. Perera,Sean P. Ferris,Tamara R. Jones,Kari Neier,Xiang Zhou,Maureen A. Sartor,Saher Sue Hammoud,Dana C. Dolinoy,Justin A. Colacino +13 more
TL;DR: This study serves as a biological reference for future single cell studies of toxicant or neuronal complications, to ultimately characterize the molecular basis by which Pb influences cognition and behavior.
Journal ArticleDOI
meQTL mapping in the GENOA study reveals genetic determinants of DNA methylation in African Americans
Lulu Shang,Wei Zhao,Yi Wang,Zhengrong Li,Minjung A. Kho,Thomas H. Mosley,Sharon L.R. Kardia,Jennifer A. Smith,Xiang Zhou +8 more
TL;DR: The authors performed a large-scale cis-meQTL mapping study in 961 African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA) study, identifying a total of 4,565,687 cis-acting meQTLs in 320,965 meCpGs.
Posted ContentDOI
On Cross-ancestry Cancer Polygenic Risk Scores
Lars G. Fritsche,Ying Ma,Daiwei Zhang,Maxwell Salvatore,Seunggeun Lee,Seunggeun Lee,Xiang Zhou,Bhramar Mukherjee +7 more
TL;DR: In this paper, the authors compared the utility of breast and prostate cancer polygenic risk scores derived from external European-ancestry-based GWAS across African, East Asian, European, and South Asian ancestry groups.