Y
Yang Liu
Researcher at Baker IDI Heart and Diabetes Institute
Publications - 7
Citations - 440
Yang Liu is an academic researcher from Baker IDI Heart and Diabetes Institute. The author has contributed to research in topics: Myocardial infarction & Macrophage migration inhibitory factor. The author has an hindex of 6, co-authored 7 publications receiving 379 citations. Previous affiliations of Yang Liu include Monash University.
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Journal ArticleDOI
Standardizing a simpler, more sensitive and accurate tail bleeding assay in mice
TL;DR: Determination of bleeding pattern and bleeding volume, in addition to bleeding time, improved the sensitivity and accuracy of this assay, particularly when platelet function is partially inhibited.
Journal ArticleDOI
Novel Role of Platelets in Mediating Inflammatory Responses and Ventricular Rupture or Remodeling Following Myocardial Infarction
Yang Liu,Xiao-Ming Gao,Lu Fang,N. Jennings,Yidan Su,Qi Xu,Andre L. Samson,Helen Kiriazis,Xin-Feng Wang,Leonard Shan,Sharelle Anne Sturgeon,Robert L. Medcalf,Shaun P. Jackson,Anthony M. Dart,Xiao-Jun Du +14 more
TL;DR: Platelets play a pivotal role in promoting systemic and cardiac inflammatory responses post-MI, contributing to regional inflammation, ventricular remodeling, and rupture, and antiplatelet therapy reduces the severity of inflammation and risk of post- MI complications.
Journal ArticleDOI
Deletion of macrophage migration inhibitory factor protects the heart from severe ischemia-reperfusion injury: a predominant role of anti-inflammation.
Xiao-Ming Gao,Yang Liu,David A. White,Yidan Su,Brian G. Drew,Clinton R. Bruce,Helen Kiriazis,Qi Xu,N. Jennings,Alex Bobik,Mark A. Febbraio,Bronwyn A. Kingwell,Richard Bucala,Gunter Fingerle-Rowson,Anthony M. Dart,Eric F Morand,Xiao-Jun Du +16 more
TL;DR: It is shown that duration of both ischemia and reperfusion is a determinant for the degree of regional inflammation and tissue damage and MIF inhibitory therapy may be a novel strategy to protect the heart against severe I/R injury.
Journal ArticleDOI
Macrophage Migration Inhibitory Factor for the Early Prediction of Infarct Size
William Chan,David A. White,Xin‐Yu-Y. Wang,Ru‐Feng-F. Bai,Yang Liu,Hai‐Yi-Y. Yu,You‐Yi-Y. Zhang,Fenling Fan,Hans G. Schneider,Stephen J. Duffy,Stephen J. Duffy,Andrew J. Taylor,Andrew J. Taylor,Xiao‐Jun-J. Du,Xiao‐Jun-J. Du,Wei Gao,Xiao‐Ming-M. Gao,Xiao‐Ming-M. Gao,Anthony M. Dart,Anthony M. Dart,Anthony M. Dart +20 more
TL;DR: Plasma MIF levels are elevated in a high proportion of STEMI patients at the first obtainable sample and these levels are predictive of final infarct size and the extent of cardiac remodeling.
Journal ArticleDOI
Role of intramural platelet thrombus in the pathogenesis of wall rupture and intra-ventricular thrombosis following acute myocardial infarction
Xiao-Jun Du,Leonard Shan,Xiao-Ming Gao,Helen Kiriazis,Yang Liu,Abhirup Lobo,Geoffrey A. Head,Anthony M. Dart +7 more
TL;DR: IMT is a key pathological element in the infarcted heart closely associated with the complications of rupture and LVT and may propagate towards the ventricular chamber to trigger LVT.