Y
Ying Hu
Researcher at National Institutes of Health
Publications - 181
Citations - 17475
Ying Hu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 46, co-authored 156 publications receiving 14842 citations. Previous affiliations of Ying Hu include University of Maryland, Baltimore & Thomas Jefferson University.
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Journal ArticleDOI
Modifier locus mapping of a transgenic F2 mouse population identifies CCDC115 as a novel aggressive prostate cancer modifier gene in humans.
Jean M. Winter,Jean M. Winter,Natasha L. Curry,Derek M. Gildea,Kendra A. Williams,Minnkyong Lee,Ying Hu,Nigel P.S. Crawford +7 more
TL;DR: It is demonstrated how modifier locus mapping in mouse models of PC, coupled with in silico analyses of human PC datasets, can reveal novel germline modifier genes of aggressive PC.
Journal Article
Hemochromatosis Gene Mutations and Distal Adenomatous Colorectal Polyps
Katherine A. McGlynn,Lori C. Sakoda,Ying Hu,Robert E. Schoen,Robert S. Bresalier,Meredith Yeager,Stephen J. Chanock,Richard B. Hayes,Kenneth H. Buetow +8 more
TL;DR: The results do not support a relationship between HFE heterozygosity and risk of advanced distal adenoma and the relationship was affected by dietary iron intake.
Journal ArticleDOI
Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study.
Justyna Bartoszko,Kevin E. Thorpe,Kevin E. Thorpe,Andreas Laupacis,Duminda N. Wijeysundera,Paul S. Myles,Mark A Shulman,S. Wallace,Catherine Farrington,Bryony A. Thompson,M. Ellis,B. Borg,R Kerridge,J. Douglas,J. Brannan,Jeffrey J. Pretto,M.G. Godsall,N. Beauchamp,S. Allen,A. Kennedy,E. Wright,J. Malherbe,Hilmy Ismail,Bernhard Riedel,A. Melville,H. Sivakumar,A. Murmane,K. Kenchington,Y. Kirabiyik,Usha Gurunathan,Christopher A. Stonell,K. Brunello,K. Steele,Oystein Tronstad,Philip Masel,Annette Dent,E. Smith,A. Bodger,M. Abolfathi,P. Sivalingam,A. Hall,Thomas Painter,S. Macklin,Adrian D. Elliott,A.M. Carrera,N Terblanche,S. Pitt,J. Samuels,C. Wilde,Kate Leslie,A. MacCormick,D. Bramley,A.M. Southcott,John Grant,Hugh Taylor,S. Bates,M. Towns,A. Tippett,Fiona H. Marshall,C.D. Mazer,J. Kunasingam,A. Yagnik,C. Crescini,S. Yagnik,Colin J. L. McCartney,Stephen Choi,P. Somascanthan,K. Flores,W.S. Beattie,Keyvan Karkouti,Hance Clarke,Angela Jerath,Stuart A. McCluskey,Marcin Wasowicz,John Granton,L. Day,J. Pazmino-Canizares,Paul Oh,R. Belliard,L. Lee,K. Dobson,Vincent W. S. Chan,Richard Brull,N. Ami,M. Stanbrook,K. Hagen,D. Campbell,Timothy G. Short,J. Van Der Westhuizen,Kushlin Higgie,Helen A. Lindsay,R. Jang,C. Wong,D. Mcallister,M. Ali,J. Kumar,Ellen Waymouth,Chang Joon Kim,J. Dimech,M. Lorimer,J. Tai,R. Miller,R. Sara,A. Collingwood,S. Olliff,S. Gabriel,H. Houston,P. Dalley,S. Hurford,A. Hunt,L. Andrews,L. Navarra,A. Jason-Smith,H. Thompson,N. McMillan,G. Back,B. L. Croal,M. Lum,Daniel Martin,Sarah-Naomi James,Helder Filipe,M. Pinto,S. Kynaston,Rupert M Pearse,Tom E.F. Abbott,M. Phull,C. Beilstein,Phoebe Bodger,K. Everingham,Ying Hu,E. Niebrzegowska,C. Corriea,Thais Creary,M. Januszewska,T. Ahmad,J. Whalley,R. Haslop,J. McNeil,A. Brown,N. MacDonald,M. Pakats,K. Greaves,Shaman Jhanji,R. Raobaikady,Ethel Black,M. Rooms,H. Lawrence,M. Koutra,K. Pirie,M. Gertsman,S. Jack,M. Celinski,Denny Z. H. Levett,Marc Edwards,K. Salmon,C. Bolger,L. Loughney,L. Seaward,H. Collins,B. Tyrell,N. Tantony,K. Golder,Gareth L. Ackland,L. Gallego-Paredes,Anna Reyes,A. Gutierrez del Arroyo,A. Raj,R. Lifford,Brian H Cuthbertson,Elizabeth B. Torres,Althea Ambosta,M. Melo,Muhammad Mamdani,Mpw Grocott,Graham S. Hillis,Harindra C. Wijeysundera +175 more
TL;DR: Both anaemia and poor functional capacity are associated with postoperative complications and may therefore be modifiable targets for preoperative optimisation.
Journal ArticleDOI
Transcriptome Profiling of Pediatric Core Binding Factor AML.
Chih Hao Hsu,Cu Nguyen,Chunhua Yan,Rhonda E. Ries,Qing Rong Chen,Ying Hu,Fabiana Ostronoff,Derek L. Stirewalt,George Komatsoulis,Shawn Levy,Daoud Meerzaman,Soheil Meshinchi +11 more
TL;DR: These data provide comprehensive transcriptome profiling of CBF-AML and delineate genes and pathways that are differentially expressed, providing insights into the shared biology as well as differences in the two CBF subsets.
Journal ArticleDOI
MLIP causes recessive myopathy with rhabdomyolysis, myalgia and baseline elevated serum creatine kinase.
Osorio Lopes Abath Neto,Osorio Lopes Abath Neto,Livija Medne,Sandra Donkervoort,María Elena Rodríguez-García,Véronique Bolduc,Ying Hu,Eleonora Guadagnin,A. Reghan Foley,John F. Brandsema,Allan M. Glanzman,Gihan Tennekoon,Mariarita Santi,Justin H Berger,Lynn A. Megeney,Hirofumi Komaki,Michio Inoue,Francisco Javier Cotrina-Vinagre,Aurelio Hernández-Laín,Elena Martín-Hernández,Linford Williams,S. Borell,David Schorling,Kimberly Y. Lin,Konstantinos Kolokotronis,Uta Lichter-Konecki,Janbernd Kirschner,Ichizo Nishino,Brenda Banwell,Francisco Martínez-Azorín,Patrick G. Burgon,Carsten G. Bönnemann +31 more
TL;DR: In this article, biallelic truncating variants were predicted to result in disruption of the nuclear localizing signal of MLIP and reduced overall RNA expression levels of the predominant MLIP isoform.