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Yussanne Ma
Researcher at BC Cancer Agency
Publications - 8
Citations - 6967
Yussanne Ma is an academic researcher from BC Cancer Agency. The author has contributed to research in topics: DNA methylation & Neuroblastoma RAS viral oncogene homolog. The author has an hindex of 4, co-authored 8 publications receiving 5349 citations. Previous affiliations of Yussanne Ma include National Institutes of Health.
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Journal ArticleDOI
Genomic Classification of Cutaneous Melanoma
Rehan Akbani,Kadir C. Akdemir,B. Arman Aksoy,Monique Albert,Adrian Ally,Samirkumar B. Amin,Harindra Arachchi,Arshi Arora,J. Todd Auman,Brenda Ayala,Julien Baboud,Miruna Balasundaram,Saianand Balu,Nandita Barnabas,John M. S. Bartlett,Pam Bartlett,Boris C. Bastian,Stephen B. Baylin,Madhusmita Behera,Dmitry Belyaev,Christopher C. Benz,Brady Bernard,Rameen Beroukhim,Natalie Bir,Aaron D. Black,Tom Bodenheimer,Lori Boice,Genevieve M. Boland,Riccardo Bono,Moiz S. Bootwalla,Marcus Bosenberg,Jay Bowen,Reanne Bowlby,Christopher A. Bristow,Laura Brockway-Lunardi,Denise Brooks,Jakub Brzezinski,Wiam Bshara,Elizabeth Buda,William R. Burns,Yaron S.N. Butterfield,Michael Button,Tiffany L. Calderone,Giancarlo Antonini Cappellini,Candace D. Carter,Scott L. Carter,Lynn Cherney,Andrew D. Cherniack,Aaron Chevalier,Lynda Chin,Juok Cho,Raymond J. Cho,Yoon La Choi,Andy Chu,Sudha Chudamani,Kristian Cibulskis,Giovanni Ciriello,Amanda Clarke,Stephen Coons,Leslie Cope,Daniel Crain,Erin Curley,Ludmila Danilova,Stefania D'Atri,Tanja Davidsen,Michael A. Davies,Keith A. Delman,John A. Demchok,Qixia A. Deng,Yonathan Lissanu Deribe,Noreen Dhalla,Rajiv Dhir,Daniel DiCara,Michael Dinikin,Michael Dubina,J. Stephen Ebrom,Sophie Egea,Greg Eley,Jay Engel,Jennifer Eschbacher,Konstantin V. Fedosenko,Ina Felau,Timothy R. Fennell,Martin L. Ferguson,Sheila Fisher,Keith T. Flaherty,Scott Frazer,Jessica Frick,Victoria Fulidou,Stacey Gabriel,Jianjiong Gao,Johanna Gardner,Levi A. Garraway,Julie M. Gastier-Foster,Carmelo Gaudioso,Nils Gehlenborg,Giannicola Genovese,Mark Gerken,Jeffrey E. Gershenwald,Gad Getz,Carmen Gomez-Fernandez,Thomas Gribbin,Jonna Grimsby,Benjamin Gross,Ranabir Guin,Tony Gutschner,Angela Hadjipanayis,Ruth Halaban,Benjamin Hanf,David Haussler,Lauren E. Haydu,D. Neil Hayes,Nicholas K. Hayward,David I. Heiman,Lynn M. Herbert,James G. Herman,Peter Hersey,Katherine A. Hoadley,Eran Hodis,Robert A. Holt,Dave S.B. Hoon,Susan Hoppough,Alan P. Hoyle,Franklin W. Huang,Mei Huang,Sharon K. Huang,Carolyn M. Hutter,Matthew Ibbs,Lisa Iype,Anders Jacobsen,Valerie Jakrot,Alyssa Janning,William R. Jeck,Stuart R. Jefferys,Mark A. Jensen,Corbin D. Jones,Steven J.M. Jones,Zhenlin Ju,Hojabr Kakavand,Hyojin Kang,Richard F. Kefford,Fadlo R. Khuri,Jaegil Kim,John M. Kirkwood,Joachim Klode,Anil Korkut,Konstanty Korski,Michael Krauthammer,Raju Kucherlapati,Lawrence N. Kwong,Witold Kycler,Marc Ladanyi,Phillip H. Lai,Peter W. Laird,Eric S. Lander,Michael S. Lawrence,Alexander J. Lazar,Radoslaw Łaźniak,Darlene Lee,Jeffrey E. Lee,Junehawk Lee,Kenneth K. Lee,Semin Lee,William Lee,Ewa Leporowska,Kristen M. Leraas,Haiyan I. Li,Tara M. Lichtenberg,Lee Lichtenstein,Pei Lin,Shiyun Ling,Jia Liu,Ouida Liu,Wen-Bin Liu,Georgina V. Long,Yiling Lu,Singer Ma,Yussanne Ma,Andrzej Mackiewicz,Harshad S. Mahadeshwar,Jared Malke,David Mallery,Georgy Manikhas,Graham J. Mann,Marco A. Marra,Brenna Matejka,Michael Mayo,Sousan Mehrabi,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,John P. Miller,Martin L. Miller,Gordon B. Mills,Fedor Moiseenko,Richard A. Moore,Scott Morris,Carl Morrison,Donald L. Morton,Stergios J. Moschos,Lisle E. Mose,Florian L. Muller,Andrew J. Mungall,D. Murawa,Pawel Murawa,Bradley A. Murray,Luigi Nezi,Sam Ng,Dana Nicholson,Michael S. Noble,Adeboye Osunkoya,Taofeek K. Owonikoko,Bradley A. Ozenberger,Elena Pagani,Oxana Paklina,Angeliki Pantazi,Michael Parfenov,Jeremy Parfitt,Peter J. Park,Woong-Yang Park,Joel S. Parker,Francesca Passarelli,Robert Penny,Charles M. Perou,Todd Pihl,Olga Potapova,Victor G. Prieto,Alexei Protopopov,Michael J. Quinn,Amie Radenbaugh,Kunal Rai,Suresh Ramalingam,Ayush T. Raman,Nilsa C. Ramirez,Ricardo Ramirez,Uma Rao,W. Kimryn Rathmell,Xiaojia Ren,Sheila Reynolds,Jeffrey Roach,A. Gordon Robertson,Merrick I. Ross,Jason Roszik,Giandomenico Russo,Gordon Saksena,Charles Saller,Yardena Samuels,Chris Sander,Cindy Sander,George E. Sandusky,Netty Santoso,Melissa Saul,Robyn P. M. Saw,Dirk Schadendorf,Jacqueline E. Schein,Nikolaus Schultz,Steven E. Schumacher,Charles Schwallier,Richard A. Scolyer,Jonathan G. Seidman,Pedamallu Chandra Sekhar,Harmanjatinder S. Sekhon,Yasin Senbabaoglu,Sahil Seth,Kerwin F. Shannon,Samantha Sharpe,Norman E. Sharpless,Kenna R. Mills Shaw,Candace Shelton,Troy Shelton,Ronglai Shen,Margi Sheth,Yan Shi,Carolyn J. Shiau,Ilya Shmulevich,Gabriel Sica,Janae V. Simons,Rileen Sinha,Payal Sipahimalani,Heidi J. Sofia,Matthew G. Soloway,Xingzhi Song,Carrie Sougnez,Andrew J. Spillane,Arkadiusz Spychała,Jonathan R. Stretch,Joshua M. Stuart,Wiktoria Maria Suchorska,Antje Sucker,S. Onur Sumer,Yichao Sun,Maria Synott,Barbara Tabak,Teresa R. Tabler,Angela Tam,Donghui Tan,Jiabin Tang,Roy Tarnuzzer,Katherine Tarvin,Honorata Tatka,Barry S. Taylor,M. Teresiak,Nina Thiessen,John F. Thompson,Leigh B. Thorne,Vesteinn Thorsson,Jeffrey M. Trent,Timothy J. Triche,Kenneth Y. Tsai,Peiling Tsou,David Van Den Berg,Eliezer M. Van Allen,Umadevi Veluvolu,Roeland Verhaak,Douglas Voet,Olga Voronina,Vonn Walter,Jessica Walton,Yunhu Wan,Yuling Wang,Zhining Wang,Scot Waring,Ian R. Watson,Nils Weinhold,John N. Weinstein,Daniel J. Weisenberger,Peter White,Matthew D. Wilkerson,James S. Wilmott,Lisa Wise,Maciej Wiznerowicz,Scott E. Woodman,Chang Jiun Wu,Chia Chin Wu,Junyuan Wu,Ye Wu,Ruibin Xi,Andrew Wei Xu,Da Yang,Liming Yang,Lixing Yang,Travis I. Zack,Jean C. Zenklusen,Hailei Zhang,Jianhua Zhang,Wei Zhang,Xiaobei Zhao,Jingchun Zhu,Kelsey Zhu,Lisa Zimmer,Erik Zmuda,Lihua Zou +351 more
TL;DR: This clinicopathological and multi-dimensional analysis suggests that the prognosis of melanoma patients with regional metastases is influenced by tumor stroma immunobiology, offering insights to further personalize therapeutic decision-making.
Journal ArticleDOI
The Molecular Taxonomy of Primary Prostate Cancer
Adam Abeshouse,Jaeil Ahn,Rehan Akbani,Adrian Ally,Samirkumar B. Amin,Christopher D. Andry,Matti Annala,Armen Aprikian,Joshua Armenia,Arshi Arora,J. Todd Auman,Miruna Balasundaram,Saianand Balu,Christopher E. Barbieri,Thomas L. Bauer,Christopher C. Benz,Alain Bergeron,Rameen Beroukhim,Mario Berrios,Adrian Bivol,Tom Bodenheimer,Lori Boice,Moiz S. Bootwalla,Rodolfo Borges Dos Reis,Paul C. Boutros,Jay Bowen,Reanne Bowlby,Jeff Boyd,Robert K. Bradley,Anne Breggia,Fadi Brimo,Christopher A. Bristow,Denise Brooks,Bradley M. Broom,Alan H. Bryce,Glenn Bubley,Eric J. Burks,Yaron S.N. Butterfield,Michael Button,David Canes,Carlos Gilberto Carlotti,Rebecca Carlsen,Michel Carmel,Peter R. Carroll,Scott L. Carter,Richard Cartun,Brett S. Carver,June M. Chan,Matthew T. Chang,Yu Chen,Andrew D. Cherniack,Simone Chevalier,Lynda Chin,Juok Cho,Andy Chu,Eric Chuah,Sudha Chudamani,Kristian Cibulskis,Giovanni Ciriello,Amanda Clarke,Matthew R. Cooperberg,Niall M. Corcoran,Anthony J. Costello,Janet E. Cowan,Daniel Crain,Erin Curley,Kerstin David,John A. Demchok,Francesca Demichelis,Noreen Dhalla,Rajiv Dhir,Alexandre Doueik,Bettina F. Drake,Heidi Dvinge,Natalya Dyakova,Ina Felau,Martin L. Ferguson,Scott Frazer,Stephen J. Freedland,Yao Fu,Stacey Gabriel,Jianjiong Gao,Johanna Gardner,Julie M. Gastier-Foster,Nils Gehlenborg,Mark Gerken,Mark Gerstein,Gad Getz,Andrew K. Godwin,Anuradha Gopalan,Markus Graefen,Kiley Graim,Thomas Gribbin,Ranabir Guin,Manaswi Gupta,Angela Hadjipanayis,Syed Haider,Lucie Hamel,D. Neil Hayes,David I. Heiman,Julian M. Hess,Katherine A. Hoadley,Andrea Holbrook,Robert A. Holt,Antonia H. Holway,Christopher M. Hovens,Alan P. Hoyle,Mei Huang,Carolyn M. Hutter,Michael Ittmann,Lisa Iype,Stuart R. Jefferys,Corbin D. Jones,Steven J.M. Jones,Hartmut Juhl,Andre Kahles,Christopher J. Kane,Katayoon Kasaian,Michael Kerger,Ekta Khurana,Jaegil Kim,Robert J. Klein,Raju Kucherlapati,Louis Lacombe,Marc Ladanyi,Phillip H. Lai,Peter W. Laird,Eric S. Lander,Mathieu Latour,Michael S. Lawrence,Kevin Lau,Tucker W. LeBien,Darlene Lee,Semin Lee,Kjong-Van Lehmann,Kristen M. Leraas,Ignaty Leshchiner,Robert Leung,John A. Libertino,Tara M. Lichtenberg,Pei Lin,W. Marston Linehan,Shiyun Ling,Scott M. Lippman,Jia Liu,Wen-Bin Liu,Lucas Lochovsky,Massimo Loda,Christopher J. Logothetis,Laxmi Lolla,Teri A. Longacre,Yiling Lu,Jianhua Luo,Yussanne Ma,Harshad S. Mahadeshwar,David Mallery,Armaz Mariamidze,Marco A. Marra,Michael Mayo,Shannon J. McCall,Ginette McKercher,Shaowu Meng,Anne Marie Mes-Masson,Maria J. Merino,Matthew Meyerson,Piotr A. Mieczkowski,Gordon B. Mills,Kenna R. Mills Shaw,Sarah Minner,Alireza Moinzadeh,Richard A. Moore,Scott Morris,Carl Morrison,Lisle E. Mose,Andrew J. Mungall,Bradley A. Murray,Jerome Myers,Rashi Naresh,Joel Nelson,Mark Nelson,Peter S. Nelson,Yulia Newton,Michael S. Noble,Houtan Noushmehr,Matti Nykter,Angeliki Pantazi,Michael Parfenov,Peter J. Park,Joel S. Parker,Joseph Paulauskis,Robert Penny,Charles M. Perou,Alain Piché,Todd Pihl,Peter A. Pinto,Davide Prandi,Alexei Protopopov,Nilsa C. Ramirez,Arvind Rao,W. Kimryn Rathmell,Gunnar Rätsch,Xiaojia Ren,Victor E. Reuter,Sheila Reynolds,Suhn K. Rhie,Kimberly Rieger-Christ,Jeffrey Roach,A. Gordon Robertson,Brian D. Robinson,Mark A. Rubin,Fred Saad,Sara Sadeghi,Gordon Saksena,Charles Saller,Andrew Salner,Francisco Sanchez-Vega,Chris Sander,George E. Sandusky,Guido Sauter,Andrea Sboner,Peter T. Scardino,Eleonora Scarlata,Jacqueline E. Schein,Thorsten Schlomm,Laura S. Schmidt,Nikolaus Schultz,Steven E. Schumacher,Jonathan G. Seidman,Luciano Neder,Sahil Seth,Alexis Sharp,Candace Shelton,Troy Shelton,Hui Shen,Ronglai Shen,Mark E. Sherman,Margi Sheth,Yan Shi,Juliann Shih,Ilya Shmulevich,Jeffry Simko,Ronald Simon,Janae V. Simons,Payal Sipahimalani,Tara Skelly,Heidi J. Sofia,Matthew G. Soloway,Xingzhi Song,Andrea Sorcini,Carrie Sougnez,Serghei Stepa,Chip Stewart,John A. Stewart,Joshua M. Stuart,Travis Sullivan,Charlie Sun,Huandong Sun,Angela Tam,Donghui Tan,Jiabin Tang,Roy Tarnuzzer,Katherine Tarvin,Barry S. Taylor,Patrick Teebagy,Imelda Tenggara,Bernard Têtu,Ashutosh Tewari,Nina Thiessen,Timothy C. Thompson,Leigh B. Thorne,Daniela P. Tirapelli,Scott A. Tomlins,Felipe Amstalden Trevisan,Patricia Troncoso,Lawrence D. True,Maria Christina Tsourlakis,Svitlana Tyekucheva,Eliezer M. Van Allen,David Van Den Berg,Umadevi Veluvolu,Roeland Verhaak,Cathy D. Vocke,Doug Voet,Yunhu Wan,Qingguo Wang,Wenyi Wang,Zhining Wang,Nils Weinhold,John N. Weinstein,Daniel J. Weisenberger,Matthew D. Wilkerson,Lisa Wise,John S. Witte,Chia Chin Wu,Junyuan Wu,Ye Wu,Andrew Wei Xu,Shalini S. Yadav,Liming Yang,Lixing Yang,Christina Yau,Huihui Ye,Peggy Yena,Thomas Zeng,Jean C. Zenklusen,Hailei Zhang,Jianhua Zhang,Jiashan Zhang,Wei Zhang,Yi Zhong,Kelsey Zhu,Erik Zmuda +311 more
TL;DR: The Cancer Genome Atlas (TCGA) has been used for a comprehensive molecular analysis of primary prostate carcinomas as discussed by the authors, revealing substantial heterogeneity among primary prostate cancers, evident in the spectrum of molecular abnormalities and its variable clinical course.
Journal ArticleDOI
Integrated Genomic Characterization of Papillary Thyroid Carcinoma
Nishant Agrawal,Rehan Akbani,B. Arman Aksoy,Adrian Ally,Harindra Arachchi,Sylvia L. Asa,J. Todd Auman,Miruna Balasundaram,Saianand Balu,Stephen B. Baylin,Madhusmita Behera,Brady Bernard,Rameen Beroukhim,Justin A. Bishop,Aaron D. Black,Tom Bodenheimer,Lori Boice,Moiz S. Bootwalla,Jay Bowen,Reanne Bowlby,Christopher A. Bristow,Robin Brookens,Denise Brooks,Robert Bryant,Elizabeth Buda,Yaron S.N. Butterfield,Tobias Carling,Rebecca Carlsen,Scott L. Carter,Sally E. Carty,Timothy A. Chan,Amy Chen,Andrew D. Cherniack,Dorothy Cheung,Lynda Chin,Juok Cho,Andy Chu,Eric Chuah,Kristian Cibulskis,Giovanni Ciriello,Amanda Clarke,Gary L. Clayman,Leslie Cope,John A. Copland,Kyle R. Covington,Ludmila Danilova,Tanja Davidsen,John A. Demchok,Daniel DiCara,Noreen Dhalla,Rajiv Dhir,Sheliann S. Dookran,Gideon Dresdner,Jonathan V. Eldridge,Greg Eley,Adel K El-Naggar,Stephanie Eng,James A. Fagin,Timothy R. Fennell,Robert L. Ferris,Sheila Fisher,Scott Frazer,Jessica Frick,Stacey Gabriel,Ian Ganly,Jianjiong Gao,Levi A. Garraway,Julie M. Gastier-Foster,Gad Getz,Nils Gehlenborg,Ronald Ghossein,Richard A. Gibbs,Thomas J. Giordano,Karen Gomez-Hernandez,Jonna Grimsby,Benjamin Gross,Ranabir Guin,Angela Hadjipanayis,Hollie A. Harper,D. Neil Hayes,David I. Heiman,James G. Herman,Katherine A. Hoadley,Matan Hofree,Robert A. Holt,Alan P. Hoyle,Franklin W. Huang,Mei Huang,Carolyn M. Hutter,Trey Ideker,Lisa Iype,Anders Jacobsen,Stuart R. Jefferys,Corbin D. Jones,Steven J.M. Jones,Katayoon Kasaian,Electron Kebebew,Fadlo R. Khuri,Jaegil Kim,Roger Kramer,Richard Kreisberg,Raju Kucherlapati,David J. Kwiatkowski,Marc Ladanyi,Phillip H. Lai,Peter W. Laird,Eric S. Lander,Michael S. Lawrence,Darlene Lee,Eunjung Lee,Semin Lee,William Lee,Kristen M. Leraas,Tara M. Lichtenberg,Lee Lichtenstein,Pei Lin,Shiyun Ling,Jinze Liu,Wen-Bin Liu,Yingchun Liu,Virginia A. LiVolsi,Yiling Lu,Yussanne Ma,Harshad S. Mahadeshwar,Marco A. Marra,Michael Mayo,David G. McFadden,Shaowu Meng,Matthew Meyerson,Piotr A. Mieczkowski,Michael L. Miller,Gordon B. Mills,Richard A. Moore,Lisle E. Mose,Andrew J. Mungall,Bradley A. Murray,Yuri E. Nikiforov,Michael S. Noble,Akinyemi I. Ojesina,Taofeek K. Owonikoko,Bradley A. Ozenberger,Angeliki Pantazi,Michael Parfenov,Peter J. Park,Joel S. Parker,Evan O. Paull,Chandra Sekhar Pedamallu,Charles M. Perou,Jan F. Prins,Alexei Protopopov,Suresh Ramalingam,Nilsa C. Ramirez,Ricardo Ramirez,Benjamin J. Raphael,W. Kimryn Rathmell,Xiaojia Ren,Sheila Reynolds,Esther Rheinbay,Matthew D. Ringel,Michael Rivera,Jeffrey Roach,A. Gordon Robertson,Mara Rosenberg,Matthew Rosenthal,Sara Sadeghi,Gordon Saksena,Chris Sander,Netty Santoso,Jacqueline E. Schein,Nikolaus Schultz,Steven E. Schumacher,Raja R. Seethala,Jonathan G. Seidman,Yasin Senbabaoglu,Sahil Seth,Samantha Sharpe,Kenna R. Mills Shaw,John Paul Shen,Ronglai Shen,Steven I. Sherman,Margi Sheth,Yan Shi,Ilya Shmulevich,Gabriel Sica,Janae V. Simons,Rileen Sinha,Payal Sipahimalani,Robert C. Smallridge,Heidi J. Sofia,Matthew G. Soloway,Xingzhi Song,Carrie Sougnez,Chip Stewart,Petar Stojanov,Joshua M. Stuart,S. Onur Sumer,Yichao Sun,Barbara Tabak,Angela Tam,Donghui Tan,Jiabin Tang,Roy Tarnuzzer,Barry S. Taylor,Nina Thiessen,Leigh B. Thorne,Vesteinn Thorsson,R. Michael Tuttle,Christopher B. Umbricht,David Van Den Berg,Fabio Vandin,Umadevi Veluvolu,Roeland Verhaak,Michelle Vinco,Doug Voet,Vonn Walter,Zhining Wang,Scot Waring,Paul M. Weinberger,Nils Weinhold,John N. Weinstein,Daniel J. Weisenberger,David A. Wheeler,Matthew D. Wilkerson,Jocelyn Wilson,Michelle D. Williams,Daniel A. Winer,Lisa Wise,Junyuan Wu,Liu Xi,Andrew Wei Xu,Liming Yang,Lixing Yang,Travis I. Zack,Martha A. Zeiger,Dong Zeng,Jean C. Zenklusen,Ni Zhao,Hailei Zhang,Jianhua Zhang,Jiashan Zhang,Wei Zhang,Erik Zmuda,Lihua Zou +242 more
TL;DR: The genomic landscape of 496 PTCs is described and a reclassification of thyroid cancers into molecular subtypes that better reflect their underlying signaling and differentiation properties is proposed, which has the potential to improve their pathological classification and better inform the management of the disease.
Journal ArticleDOI
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
Hamid Bolouri,Jason E. Farrar,Timothy J. Triche,Rhonda E. Ries,Emilia L. Lim,Todd A. Alonzo,Todd A. Alonzo,Yussanne Ma,Richard A. Moore,Andrew J. Mungall,Marco A. Marra,Jinghui Zhang,Xiaotu Ma,Yu Liu,Yanling Liu,Jaime M. Guidry Auvil,Tanja Davidsen,Patee Gesuwan,Leandro C. Hermida,Bodour Salhia,Stephen Capone,Giridharan Ramsingh,Christian M. Zwaan,Sanne Noort,Stephen R. Piccolo,Stephen R. Piccolo,E. Anders Kolb,Alan S. Gamis,Malcolm A. Smith,Daniela S. Gerhard,Soheil Meshinchi +30 more
TL;DR: The results highlight the need for and facilitate the development of age-tailored targeted therapies for the treatment of pediatric AML.
Posted ContentDOI
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
Hamid Bolouri,Jason E. Farrar,Timothy J. Triche,Rhonda E. Ries,Emilia L. Lim,Todd A. Alonzo,Todd A. Alonzo,Yussanne Ma,Richard A. Moore,Andrew J. Mungall,Marco A. Marra,Jinghui Zhang,Xiaotu Ma,Yu Liu,Yanling Liu,Jaime M. Guidry Auvil,Tanja Davidsen,Patee Gesuwan,Leandro C. Hermida,Bodour Salhia,Stephen Capone,Giridharan Ramsingh,Christian M. Zwaan,Sanne Noort,Stephen R. Piccolo,Stephen R. Piccolo,E. Anders Kolb,Alan S. Gamis,Malcolm A. Smith,Daniela S. Gerhard,Soheil Meshinchi +30 more
TL;DR: The results highlight the need for, and facilitate the development of age-tailored targeted therapies for the treatment of pediatric AML, with a focus on zinc finger genes associated with KMT2A rearrangements.