Zaining Yun

TL;DR: The Collaborative Cross Consortium reports here on the development of a unique genetic resource population, a multiparental recombinant inbred panel derived from eight laboratory mouse inbred strains, which shows that founder haplotypes are inherited at the expected frequency.

TL;DR: It is concluded that, as with humans, pervasive regulatory variation influences complex genetic traits in mice and provide a new resource toward understanding the genetic control of transcription in mammals.

TL;DR: It is found that cis-regulatory effects play an important role in gene expression differences between strains and that the cis-Regulatory elements are more often located in 5′ and/or 3′ transcript boundaries, with no apparent preference on either 5′ or 3′ ends.

TL;DR: The RNA-seq data sets that passed quality control are available at the Sequence Read Archive (SRA) under accession SRP056236.

TL;DR: In this article , hydrogel coated membranes (HCMs) functionalized with cell-activating antibodies are produced as a tunable biomaterial for the activation of primary human T-cells.