B
Binnaz Yalcin
Researcher at French Institute of Health and Medical Research
Publications - 48
Citations - 4767
Binnaz Yalcin is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 20, co-authored 40 publications receiving 4145 citations. Previous affiliations of Binnaz Yalcin include Centre national de la recherche scientifique & University of Lausanne.
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Journal ArticleDOI
Mouse genomic variation and its effect on phenotypes and gene regulation
Thomas M. Keane,Leo Goodstadt,Petr Danecek,Michael A. White,Kim Wong,Binnaz Yalcin,Andreas Heger,Avigail Agam,Avigail Agam,Guy Slater,Martin Goodson,Nick Furlotte,Eleazar Eskin,Christoffer Nellåker,Helen Whitley,James Cleak,Deborah Janowitz,Deborah Janowitz,Polinka Hernandez-Pliego,Andrew Edwards,T G Belgard,Peter L. Oliver,Rebecca E. McIntyre,Amarjit Bhomra,Jérôme Nicod,Xiangchao Gan,Wei Yuan,L van der Weyden,Charles A. Steward,Sendu Bala,Jim Stalker,Richard Mott,Richard Durbin,Ian J. Jackson,Anne Czechanski,José Afonso Guerra-Assunção,Leah Rae Donahue,Laura G. Reinholdt,Bret A. Payseur,Chris P. Ponting,Ewan Birney,Jonathan Flint,David J. Adams +42 more
TL;DR: These sequences provide a starting point for a new era in the functional analysis of a key model organism and show that the molecular nature of functional variants and their position relative to genes vary according to the effect size of the locus.
Journal ArticleDOI
The genome architecture of the collaborative cross mouse genetic reference population
Fuad A. Iraqi,Mustafa Mahajne,Yasser Salaymah,Hani Sandovski,Hanna Tayem,Karin Vered,Lois Balmer,Michael R. Hall,Glynn Manship,Grant Morahan,Ken Pettit,Jeremy Scholten,Kathryn Tweedie,Andrew Wallace,Lakshini Weerasekera,James Cleak,Caroline Durrant,Leo Goodstadt,Richard Mott,Binnaz Yalcin,David L. Aylor,Ralph S. Baric,Timothy A. Bell,Katharine M. Bendt,J. Brennan,Jackie D. Brooks,Ryan J. Buus,James J. Crowley,John D. Calaway,Mark Calaway,Agnieszka Cholka,David B. Darr,John P. Didion,Amy Dorman,Eric T. Everett,Martin T. Ferris,Wendy Foulds Mathes,Chen Ping Fu,Terry J. Gooch,Summer G. Goodson,Lisa E. Gralinski,Stephanie D. Hansen,Mark T. Heise,Jane Hoel,Kunjie Hua,Mayanga C. Kapita,Seunggeun Lee,Alan B. Lenarcic,Eric Yi Liu,Hedi Liu,Leonard McMillan,Terry Magnuson,Kenneth F. Manly,Darla R. Miller,Deborah A. O'Brien,Fanny Odet,Isa Kemal Pakatci,Wenqi Pan,Fernando Pardo-Manuel de Villena,Charles M. Perou,Daniel Pomp,Corey R. Quackenbush,Nashiya N. Robinson,Norman E. Sharpless,Ginger D. Shaw,Jason S. Spence,Patrick F. Sullivan,Wei Sun,Lisa M. Tarantino,William Valdar,Jeremy Wang,Wei Wang,Catherine E. Welsh,Alan C. Whitmore,Tim Wiltshire,Fred A. Wright,Yuying Xie,Zaining Yun,Vasyl Zhabotynsky,Zhaojun Zhang,Fei Zou,Christine L. Powell,Jill Steigerwalt,David W. Threadgill,Elissa J. Chesler,Gary A. Churchill,Daniel M. Gatti,Ron Korstanje,Karen L. Svenson,Francis S. Collins,Nigel P.S. Crawford,Kent W. Hunter,N. Samir,P. Kelada,Bailey C.E. Peck,Karlyne M. Reilly,Urraca Tavarez,Daniel Bottomly,Robert Hitzeman,Shannon K. McWeeney,Jeffrey A. Frelinger,Harsha Krovi,Jason Phillippi,Richard A. Spritz,Lauri D. Aicher,Michael G. Katze,Elizabeth Rosenzweig,Ariel Shusterman,Aysar Nashef,Ervin I. Weiss,Yael Houri-Haddad,Morris Soller,Robert W. Williams,Klaus Schughart,Hyuna Yang,John E. French,Andrew K. Benson,Jaehyoung Kim,Ryan Legge,Soo Jen Low,Fangrui Ma,Inés Martínez,Jens Walter,Karl W. Broman,Benedikt Hallgrímsson,Ophir D. Klein,George M. Weinstock,Wesley C. Warren,Yvana V. Yang,David A. Schwartz +129 more
TL;DR: The Collaborative Cross Consortium reports here on the development of a unique genetic resource population, a multiparental recombinant inbred panel derived from eight laboratory mouse inbred strains, which shows that founder haplotypes are inherited at the expected frequency.
Journal ArticleDOI
Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data.
TL;DR: The DRD4 gene may be associated with measures of novelty seeking and impulsivity but not extraversion, and the association of the C-521T variant with these measures, if genuine, may account for up to 3% of phenotypic variance.
Journal ArticleDOI
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains
Michelle Simon,Simon Greenaway,Jacqueline K. White,Helmut Fuchs,Valerie Gailus-Durner,Sara Wells,Tania Sorg,Kim Wong,Elodie Bedu,Elizabeth J. Cartwright,Romain Dacquin,Sophia Djebali,Jeanne Estabel,Jochen Graw,Neil J. Ingham,Ian J. Jackson,Andreas Lengeling,Silvia Mandillo,Jacqueline Marvel,Hamid Meziane,Frédéric Preitner,Oliver Puk,Michel Roux,David J. Adams,Sarah Atkins,Abdel Ayadi,Lore Becker,Andrew Blake,Debra Brooker,Heather Cater,Marie-France Champy,Roy Combe,Petr Danecek,Armida Di Fenza,Hilary Gates,Anna-Karin Gerdin,Elisabetta Golini,John M. Hancock,Wolfgang Hans,Sabine M. Hölter,Tertius Hough,Pierre Jurdic,Thomas M. Keane,Hugh P. Morgan,Werner Müller,Frauke Neff,George Nicholson,Bastian Pasche,Laura-Anne Roberson,Jan Rozman,Mark Sanderson,Luis Santos,Mohammed Selloum,Carl Shannon,Anne Southwell,Glauco P. Tocchini-Valentini,Valerie E. Vancollie,Henrik Westerberg,Wolfgang Wurst,Min Zi,Binnaz Yalcin,Binnaz Yalcin,Ramiro Ramirez-Solis,Karen P. Steel,Ann-Marie Mallon,Martin Hrabě de Angelis,Yann Herault,Steve D.M. Brown +67 more
TL;DR: Comparison of C57BL/6J and C57bl/6N demonstrates a range of phenotypic differences that have the potential to impact upon penetrance and expressivity of mutational effects in these strains.
Journal ArticleDOI
Sequence-based characterization of structural variation in the mouse genome.
Binnaz Yalcin,Kim Wong,Avigail Agam,Avigail Agam,Martin Goodson,Thomas M. Keane,Xiangchao Gan,Christoffer Nellåker,Leo Goodstadt,Jérôme Nicod,Amarjit Bhomra,Polinka Hernandez-Pliego,Helen Whitley,James Cleak,Rebekah Dutton,Deborah Janowitz,Deborah Janowitz,Richard Mott,David J. Adams,Jonathan Flint +19 more
TL;DR: It is inferred that insertion of retrotransposons causes more than half of SVs, and 24 SVs are identified that disrupt coding exons, acting as rare variants of large effect on gene function.