Z
Zonghui Yuan
Researcher at Huazhong Agricultural University
Publications - 282
Citations - 9608
Zonghui Yuan is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Oxidative stress & High-performance liquid chromatography. The author has an hindex of 44, co-authored 276 publications receiving 7525 citations.
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Journal ArticleDOI
Metabolites and JAK/STAT pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox
Xu Wang,Xian-Ju Huang,Awais Ihsan,Zhaoying Liu,Huang Lingli,Huahai Zhang,Hongfei Zhang,Wen Zhou,Qin Liu,Xi-Juan Xue,Zonghui Yuan +10 more
TL;DR: The data demonstrated that high dose of MEQ apparently led to tissue impairment combined with imbalance of redox in liver, and reported the dose-dependent long-term toxicity as well as the discussion of the potential mechanism and pathways of MEZ, which raised further awareness of its toxicity following with the dose change.
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Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro.
TL;DR: The results demonstrate the use of LC/MS–IT–TOF approach appears to be rapid, efficient, and reliable in structural characterization of drug metabolites in in vitro metabolites of quinocetone.
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Effects of cyadox and olaquindox on intestinal mucosal immunity and on fecal shedding of Escherichia coli in piglets.
TL;DR: The data indicated that olaquindox and cyadox reduced the number of intestinal E. coli and suppressed E.coli-induced immune activation, which might be responsible for the enhanced growth that was observed.
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Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli.
Guyue Cheng,Bei Li,Chenxi Wang,Hongfei Zhang,Guixia Liang,Zhifei Weng,Haihong Hao,Xu Wang,Zhenli Liu,Menghong Dai,Yulian Wang,Zonghui Yuan +11 more
TL;DR: New insights are provided into the action of QdNOs in a systematic manner and the current knowledge of bacterial physiology under antibiotic stresses is increased, which may be of great value in the development of new antibiotic-potentiating strategies.
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Genotoxicity evaluation of Mequindox in different short-term tests.
Awais Ihsan,Xu Wang,Hong-Gong Tu,Wei Zhang,Menghong Dai,De-Peng Peng,Yulian Wang,Huang Lingli,Dongmei Chen,Shazia Mannan,Yanfei Tao,Zhenli Liu,Zonghui Yuan +12 more
TL;DR: It is concluded that MEQ had a strong genotoxic potential to mammalian cells in vitro as well as in vivo and its mutagenicity is slightly higher than CBX.