Institution
Chinese Academy of Fishery Sciences
Nonprofit•Beijing, China•
About: Chinese Academy of Fishery Sciences is a nonprofit organization based out in Beijing, China. It is known for research contribution in the topics: Population & Gene. The organization has 8107 authors who have published 7929 publications receiving 92095 citations. The organization is also known as: Zhōngguó shuǐchǎn Kēxuéyánjiūyuàn & Chinese Academy of Fishery Sciences.
Topics: Population, Gene, Shrimp, Genome, Mitochondrial DNA
Papers published on a yearly basis
Papers
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TL;DR: The relatively high expression of TLR genes in the immune tissues in response to the A. hydrophila challenge indicated that TLRs may play important roles in the innate immune response against gram‐negative bacteria in yellow catfish.
55 citations
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55 citations
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TL;DR: Findings indicated that cultivated bivalves may face potential threats from OsHV-1 types found in this study, which demonstrated that two clades were associated with abnormal mortalities of the scallop, Chlamys farrier and the calm, Scapharca broughtonii in China.
55 citations
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TL;DR: Results indicate that both rEta2 and pCETA2 induce specific and nonspecific immunities, however, pCEta2 induces both B cell and T cell responses, whereas rETA2 induces mainly humoral response.
55 citations
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TL;DR: The immune-relevant sequences identified here will facilitate the understanding of the mechanisms involved in the immune response and the plentiful potential SSRs and SNPs found in this study are important resources with respect to future development of a linkage map or marker assisted breeding programs for the flounder.
Abstract: Background
Japanese flounder (Paralichthys olivaceus) is an economically important marine fish in Asia and has suffered from disease outbreaks caused by various pathogens, which requires more information for immune relevant genes on genome background. However, genomic and transcriptomic data for Japanese flounder remain scarce, which limits studies on the immune system of this species. In this study, we characterized the Japanese flounder spleen transcriptome using an Illumina paired-end sequencing platform to identify putative genes involved in immunity.
Methodology/Principal Findings
A cDNA library from the spleen of P. olivaceus was constructed and randomly sequenced using an Illumina technique. The removal of low quality reads generated 12,196,968 trimmed reads, which assembled into 96,627 unigenes. A total of 21,391 unigenes (22.14%) were annotated in the NCBI Nr database, and only 1.1% of the BLASTx top-hits matched P. olivaceus protein sequences. Approximately 12,503 (58.45%) unigenes were categorized into three Gene Ontology groups, 19,547 (91.38%) were classified into 26 Cluster of Orthologous Groups, and 10,649 (49.78%) were assigned to six Kyoto Encyclopedia of Genes and Genomes pathways. Furthermore, 40,928 putative simple sequence repeats and 47, 362 putative single nucleotide polymorphisms were identified. Importantly, we identified 1,563 putative immune-associated unigenes that mapped to 15 immune signaling pathways.
Conclusions/Significance
The P. olivaceus transciptome data provides a rich source to discover and identify new genes, and the immune-relevant sequences identified here will facilitate our understanding of the mechanisms involved in the immune response. Furthermore, the plentiful potential SSRs and SNPs found in this study are important resources with respect to future development of a linkage map or marker assisted breeding programs for the flounder.
55 citations
Authors
Showing all 8142 results
Name | H-index | Papers | Citations |
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Yu Huang | 136 | 1492 | 89209 |
Meilin Liu | 117 | 827 | 52603 |
Lin Li | 104 | 2027 | 61709 |
Jian Xu | 94 | 1366 | 52057 |
Xiaolong Wang | 81 | 966 | 31455 |
Sheng Luan | 76 | 272 | 21253 |
Peng Xu | 75 | 1151 | 25005 |
Qiang Li | 73 | 856 | 30598 |
Deliang Chen | 68 | 461 | 16966 |
Chao Li | 64 | 561 | 17253 |
Min Du | 61 | 326 | 11328 |
Lei Wang | 59 | 988 | 14887 |
Quan Chen | 52 | 154 | 16697 |
Jun Li | 50 | 562 | 12002 |
James P. Barry | 49 | 162 | 10687 |