Institution
Chinese Academy of Fishery Sciences
Nonprofit•Beijing, China•
About: Chinese Academy of Fishery Sciences is a nonprofit organization based out in Beijing, China. It is known for research contribution in the topics: Population & Gene. The organization has 8107 authors who have published 7929 publications receiving 92095 citations. The organization is also known as: Zhōngguó shuǐchǎn Kēxuéyánjiūyuàn & Chinese Academy of Fishery Sciences.
Topics: Population, Gene, Shrimp, Genome, Mitochondrial DNA
Papers published on a yearly basis
Papers
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TL;DR: The obtained results indicate the vitamin E as a wildly used functional feed additive contributes potentially to alleviate high‐fat diet‐induced hepatic oxidative stress and hypoimmunity, maintain the health, and improve the broodstock management for turbot.
54 citations
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TL;DR: The results underscore the need to develop a sewage infrastructure for the treatment of effluent from integrated livestock/fish aquafarms, and suggest that open water culture-based fish farms should be located far from seriously contaminated sections of rivers.
53 citations
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TL;DR: It is concluded that the use of a number of microsatellite markers represents a realistic and effective alternative to physical tagging in a selection program and it allows the identification of parental effects on offspring performances from early life stages.
53 citations
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TL;DR: It is found that excessive glutamate challenge lead to significant reduction of Miro1 expression in spinal cord motor neurons both in vitro and in mice, and this finding suggests glutamate excitotoxicity as a likely cause of Mro1 deficiency.
Abstract: Proper transportation of mitochondria to sites with high energy demands is critical for neuronal function and survival. Impaired mitochondrial movement has been repeatedly reported in motor neurons of amyotrophic lateral sclerosis (ALS) patients and indicated as an important mechanism contributing to motor neuron degeneration in ALS. Miro1, a RhoGTPase also referred to as Rhot1, is a key regulator of mitochondrial movement linking mitochondria and motor proteins. In this study, we investigated whether the expression of Miro1 was altered in ALS patients and ALS animal models. Immunoblot analysis revealed that Miro1 was significantly reduced in the spinal cord tissue of ALS patients. Consistently, the decreased expression of Miro1 was also noted only in the spinal cord, and not in the brain tissue of transgenic mice expressing ALS-associated SOD1 G93A or TDP-43 M337V. Glutamate excitotoxicity is one of the major pathophysiological mechanisms implicated in the pathogenesis of ALS, and we found that excessive glutamate challenge lead to significant reduction of Miro1 expression in spinal cord motor neurons both in vitro and in mice. Taken together, these findings show Miro1 deficiency in ALS patients and ALS animal models and suggest glutamate excitotoxicity as a likely cause of Miro1 deficiency.
53 citations
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TL;DR: Embryotoxicity tests showed that acesulfame transformation products at the low g L(-1) level produced significant adverse effects in tail detachment, heart rate, hatching rate and survival rate during fish embryo development, and the formation of six new transformation products that have not been previously identified are shown.
53 citations
Authors
Showing all 8142 results
Name | H-index | Papers | Citations |
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Yu Huang | 136 | 1492 | 89209 |
Meilin Liu | 117 | 827 | 52603 |
Lin Li | 104 | 2027 | 61709 |
Jian Xu | 94 | 1366 | 52057 |
Xiaolong Wang | 81 | 966 | 31455 |
Sheng Luan | 76 | 272 | 21253 |
Peng Xu | 75 | 1151 | 25005 |
Qiang Li | 73 | 856 | 30598 |
Deliang Chen | 68 | 461 | 16966 |
Chao Li | 64 | 561 | 17253 |
Min Du | 61 | 326 | 11328 |
Lei Wang | 59 | 988 | 14887 |
Quan Chen | 52 | 154 | 16697 |
Jun Li | 50 | 562 | 12002 |
James P. Barry | 49 | 162 | 10687 |