Showing papers in "Vaccine in 2011"

TL;DR: Both the degree of threat experienced in the 2009 pandemic influenza outbreak and perceptions of vaccination as an effective coping strategy were associated with stronger intentions and higher uptake of vaccination, finding interventions to increase seasonal influenza vaccination in advance of a future pandemic may be an effective strategy.

TL;DR: The Brighton Collaboration GBS Working Group aims to provide a platform for future generations of GBS researchers to explore the role of language in the creative process and the role that language plays in the design ofGES.

TL;DR: The nature and strength of the immune response induced by various Toll-like receptor ligands and their ability to act as vaccine adjuvants are described and those agents for which clinical results are available are reviewed.

TL;DR: Among insured women, aged 19-26 years, those who discussed the HPV vaccine with their physician and received a recommendation were overwhelmingly more likely to be vaccinated.

TL;DR: AS03's promotion of monocytes as the principal antigen-presenting cells, and its effects on granulocytes and cytokines, may all contribute to enhancing the antigen-specific adaptive immune response.

TL;DR: It is shown that all recruited cell types take up both adjuvant and antigen to transport them to the draining lymph nodes (LNs), and compared to alum, MF59-injection lead to a more prominent neutrophil recruitment and a more efficient antigen re-localization from the injection site to the LN.

TL;DR: Multiple reasons for under- vaccination and non-vaccination were identified, indicating that a multi-faceted approach is needed to reach under-vaccinated and unvaccinated children.

TL;DR: The different steps and challenges of developing CYD TDV are discussed, from research to industrialization, and some of the challenges to the successful introduction of a dengue vaccine into immunization programs are summarized.

TL;DR: The revised survey is a valid and reliable instrument to identify vaccine-hesitant parents and Cronbach's α coefficients for the 3 sub-domain scales created by grouping the remaining 15 items were .74, .84, and .75, respectively.

TL;DR: Pneumococcal disease remains a substantial cause of morbidity and mortality even in the era of routine pediatric and adult vaccination, and the cost of pneumococcal Disease among younger working adults (18-<50) nearly equaled those ≥ 65.

TL;DR: Data from Ad5, Ad26, Ad35, and Ad48 NAb titers in 4381 individuals from North America, South America, sub-Saharan Africa, and Southeast Asia are reported to inform the clinical development of alternative serotype rAd vaccine vectors in the developing world.

TL;DR: Although there was no overall increase in intussusception following receipt of rotavirus vaccine, there was some evidence of an elevated risk following the first dose of both vaccines.

TL;DR: VAX102 was safe and induced high antibody levels to M2e at 0.3 and 1.0 μg doses and was able to induce a fourfold rise in antibody in humans, to a previously non-immunogenic, highly-conserved portion of the influenza virus.

TL;DR: This review summarises recent developments in the understanding of d Dengue pathogenesis and their relevance to dengue vaccine development.

TL;DR: The relative importance of specific CFs in achieving target product profiles for a future ETEC vaccine is demonstrated, however, heterogeneity across time, population, and region, confounded by variability in CF and toxin detection methodologies, obfuscates rational estimates for valency requirements.

TL;DR: A new 30-valent vaccine containing M protein peptides from GAS serotypes prevalent in North America and Europe was immunogenic in rabbits and evoked bactericidal antibodies against all 30 vaccine serotypes of GAS.

TL;DR: No statistically significant increased risk for any of the pre-specified adverse events after vaccination was detected in a study of over 600,000 HPV4 vaccine doses administered.

TL;DR: The role of each of the above mentioned carbohydrate antIGens in cancer growth and metastasis and vaccine attempts using these antigens will be described.

TL;DR: IPD due to PCV13-only serotypes halved in children under 2 years in the study period, and vaccine effectiveness (VE) for the new serotypes was 78% and 77% respectively although confidence intervals spanned zero.

TL;DR: Findings suggest missed clinical opportunities for HPV vaccination, and perceived barriers to vaccination may drive decisions about recommendation, and the need for age and specialty targeted practice and policy level interventions to increase HPV vaccination among US females.

TL;DR: There are enormous gaps in the understanding of porcine immunological mechanisms and processes that provide immunity to PRRSV infection and memory responses for long-term protection, and the authors should be confident that progress will be made.

TL;DR: HPV vaccination of 12-year-old males might potentially be cost-effective, particularly if female HPV vaccination coverage is low and if all potential health benefits of HPV vaccination are included in the analysis.

TL;DR: It is suggested that immunization with PCV13 has the potential to induce cross-protective responses to related serotypes not directly covered by the vaccine.

TL;DR: Since 1970, extensive epidemiology, virology, ecology and public health research has enabled better characterization of monkeypox virus and the associated human disease, and this work reviews the progress in this body of research.

TL;DR: Text message reminders were an effective intervention to increase on-time receipt of HPV2 or HPV3 in parents of adolescents 9-20 years who received HPV1 or HPV2 during the intervention period, January-June 2009.

TL;DR: Experimental immunisation of pigs with the non-virulent OURT88/3 genotype I isolate from Portugal followed by the closely related virulent OURt88/1 genotypes from Africa could confer protection against challenge with virulent isolates from Africa.

TL;DR: Anti-vaccination websites are constantly changing in response to the trends in public health and the success of vaccination, and effective vaccine support may be better served by including more emotionally compelling content.

TL;DR: Results indicate that vaccination with outer membrane vesicles may be a viable strategy for preventing A. baumannii infection.

TL;DR: It is demonstrated that the mode of secretion and trafficking can influence the immunogenicity of different human TAAs, and may explain the lack of immunogenicicity of non-mutated TAAs found in cancer patients, and suggested that exosomal targeting could enhance future anti-tumor vaccination protocols.

TL;DR: A(H1N1) vaccination is strongly associated with age, urbanicity, perceiving the A( H1N 1) vaccine as safe and seasonal flu vaccine uptake and perceptions of safety and season flu vaccination show the strongest associations with A(H 1N1)-related beliefs and seasonal vaccination.