Cornell University

About: Cornell University is a education organization based out in Ithaca, New York, United States. It is known for research contribution in the topics: Population & Gene. The organization has 102246 authors who have published 235546 publications receiving 12283673 citations. The organization is also known as: Cornell & CUI.

Femtosecond relaxation dynamics of large molecules.

Abstract: The ultrafast relaxation in solution of two large organic molecules, malachite green and nile blue 690, has been investigated with the equal-pulse correlation technique. In addition to previously known picosecond processes, we have observed fast initial exponential decays (less than 100 fs) and damped sinusoidal oscillation over intermediate time delays. We believe that the latter behavior, the first such decay observed on a femtosecond time scale for any material, represents quantum beats.

Fast parallel matrix and GCD computations

Abstract: We present parallel algorithms to compute the determinant and characteristic polynomial of n×n-matrices and the gcd of polynomials of degree ≤n. The algorithms use parallel time O(log2n) and a polynomial number of processors. We also give a fast parallel Las Vegas algorithm for the rank of matrices. All algorithms work over arbitrary fields.

Identification and quantitation of lipid C=C location isomers: A shotgun lipidomics approach enabled by photochemical reaction.

Abstract: The field of lipidomics has been significantly advanced by mass spectrometric analysis. The distinction and quantitation of the unsaturated lipid isomers, however, remain a long-standing challenge. In this study, we have developed an analytical tool for both identification and quantitation of lipid C=C location isomers from complex mixtures using online Paterno–Buchi reaction coupled with tandem mass spectrometry (MS/MS). The potential of this method has been demonstrated with an implementation into shotgun lipid analysis of animal tissues. Among 96 of the unsaturated fatty acids and glycerophospholipids identified from rat brain tissue, 50% of them were found as mixtures of C=C location isomers; for the first time, to our knowledge, the quantitative information of lipid C=C isomers from a broad range of classes was obtained. This method also enabled facile cross-tissue examinations, which revealed significant changes in C=C location isomer compositions of a series of fatty acids and glycerophospholipid (GP) species between the normal and cancerous tissues.