Hong Kong University of Science and Technology

About: Hong Kong University of Science and Technology is a education organization based out in Hong Kong, Hong Kong, China. It is known for research contribution in the topics: Computer science & Catalysis. The organization has 20126 authors who have published 52428 publications receiving 1965915 citations. The organization is also known as: HKUST & The Hong Kong University of Science and Technology.

Specific Light-Up Bioprobe with Aggregation-Induced Emission and Activatable Photoactivity for the Targeted and Image-Guided Photodynamic Ablation of Cancer Cells†

Abstract: Activatable photosensitizers (PSs) have been widely used for the simultaneous fluorescence imaging and photodynamic ablation of cancer cells. However, the ready aggregation of traditional PSs in aqueous media can lead to fluorescence quenching as well as reduced phototoxicity even in the activated form. We have developed a series of PSs that show aggregation-enhanced emission and phototoxicity and thus the exact opposite behavior to that of previously reported PSs. We further developed a dual-targeted enzyme-activatable bioprobe based on the optimized photosensitizer and describe simultaneous light-up fluorescence imaging and activated photodynamic therapy for specific cancer cells. The design of smart probes should thus open new opportunities for targeted and image-guided photodynamic therapy.

k-automorphism: a general framework for privacy preserving network publication

Abstract: The growing popularity of social networks has generated interesting data management and data mining problems. An important concern in the release of these data for study is their privacy, since social networks usually contain personal information. Simply removing all identifiable personal information (such as names and social security number) before releasing the data is insufficient. It is easy for an attacker to identify the target by performing different structural queries. In this paper we propose k-automorphism to protect against multiple structural attacks and develop an algorithm (called KM) that ensures k-automorphism. We also discuss an extension of KM to handle "dynamic" releases of the data. Extensive experiments show that the algorithm performs well in terms of protection it provides.

Supramolecular materials based on AIE luminogens (AIEgens): construction and applications

Abstract: The emergence of aggregation-induced emission luminogens (AIEgens) has significantly stimulated the development of luminescent supramolecular materials because their strong emissions in the aggregated state have resolved the notorious obstacle of the aggregation-caused quenching (ACQ) effect, thereby enabling AIEgen-based supramolecular materials to have a promising prospect in the fields of luminescent materials, sensors, bioimaging, drug delivery, and theranostics. Moreover, in contrast to conventional fluorescent molecules, the configuration of AIEgens is highly twisted in space. Investigating AIEgens and the corresponding supramolecular materials provides fundamental insights into the self-assembly of nonplanar molecules, drastically expands the building blocks of supramolecular materials, and pushes forward the frontiers of supramolecular chemistry. In this review, we will summarize the basic concepts, seminal studies, recent trends, and perspectives in the construction and applications of AIEgen-based supramolecular materials with the hope to inspire more interest and additional ideas from researchers and further advance the development of supramolecular chemistry.

Expatriate Knowledge Transfer, Subsidiary Absorptive Capacity, and Subsidiary Performance

Abstract: In this study, we theoretically identify three dimensions of expatriate competenciesability, motivation, and opportunity seeking—for knowledge transfer. Integrating the ability-motivation-opportunity framework and the absorptive capacity perspective, we propose that expatriate competencies in knowledge transfer influence a subsidiary's performance through the knowledge received by the subsidiary, but tbat this indirect enect is stronger when subsidiary absorptive capacity is greater. We collected multisource, time-lagged data from 162 British subsidiaries of Taiwanese multinational nrms. The results support our hypotheses. Overall, we contribute to expatriation theory and research by revealing specinc expatriate competencies as well as identifying boundary conditions for successful expatriate knowledge transfer.

Effects of surfactant treatment on mechanical and electrical properties of CNT/epoxy nanocomposites

Abstract: Surfactant has been successfully applied to enhance the dispersion of carbon nanotubes (CNTs) in polymer and the properties of nanocomposite. CNTs were treated with a nonionic surfactant Triton X-100, and its effects on dispersion state, surface chemistry, structure and morphology of CNTs, as well as on the thermomechanical, mechanical and electrical properties of CNT/epoxy nanocomposites were evaluated. The mechanical properties such as impact fracture toughness, flexural strength and modulus, the thermomechanical properties, as well as the electrical conductivity of the nanocomposite all showed significant improvements after the treatment. The above observations are attributed to the “bridging” effects between the CNT and epoxy, which are introduced by the hydrophobic and hydrophilic segments of the nonionic surfactant. The enhanced interfacial interactions gave rise to improved dispersion and wetting of CNTs in polymer matrix, enhancing the mechanical and fracture properties of the nanocomposite. Unlike chemical functionalization techniques, however, the surfactant treatment exhibited little adverse effect on electrical conducting behavior of the nanocomposite.