Jessore University of Science & Technology

About: Jessore University of Science & Technology is a based out in . It is known for research contribution in the topics: Adsorption & Population. The organization has 811 authors who have published 974 publications receiving 10471 citations.

Trema orientalis (Linn.) leaves promotes anticancer activity in Ehrlich ascites carcinoma (EAC) in Swiss albino mice.

Abstract: Background The in vivo anticancer effect of the Trema orientalis leaves crude methanol extract (TLME) was screened against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. Materials and methods The cytotoxic activity of TLME was determined in vitro by the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. The growth inhibitory activity and morphological alterations were determined by the hemocytometer counting of the EAC cells using trypan blue dye. The apoptotic cells were assessed by DAPI (4',6-diamidino-2-phenylindole) staining. The hematological and biochemical parameters of experimental mice were also estimated. Results After treatment with the TLME, the viable tumor cell count, morphological changes and nuclear damages of the EAC cells were observed along with the hematological parameters of the experimental mice. The LD50 of TLME was 3120.650 mg/kg body weight, and this extract was proven to be safe at a dose of as high as 800 mg/kg body weight. The oral administration of the TLME at 400 mg/kg body weight resulted in approximately 59% tumor cell growth inhibition compared with the control mice, with considerable apoptotic features, including membrane blebbing, chromatin condensation, nuclear fragmentation and aggregation of the apoptotic bodies in DAPI staining under a fluorescence microscope. The TLME also dose-dependently restored the altered hematological parameters to approximately normal levels. The TLME exhibited bolstering cytotoxic effect against the EAC cell with the IC50 value of 29.952 ± 1.816 μg/mL. Conclusion The TLME has potential as a natural anti-cancer product with apoptosis induction property and cytotoxicity against carcinoma cells.

The activities of Bangladesh water development board on the social environment of Bhadrabila union, Narail sadar upazila, Bangladesh

Abstract: The study was conducted at Bhadrabila union, Narail sadar upazila, Narail in Bangladesh. The study period was carried out during September to December, 2013. In the selected areas, the study was conducted on 375 persons. The collected information was totally interview and observation based study. In the study area the highest age distribution was 50% in 21-40 years. The second highest was 39% for 41-60 years. The third highest was 7% for the year of 1-20. The lowest age distribution was for the year of 60 and above. This study found that the highest respondents of 39% are the member of 3-4 family member range. 32% respondents are in the member of 5-6 family member range. 12% respondents are in the member of 7-8 family member range. This study represent that 18% houses were kacha, 27% houses were tin shade 29% half building and 26% house were building. Almost 3% respondents were in class 1-3, 31% were in class 4-6, 46% were in between class 7-9, 10% in S.S.C level and left 9% were in above S.S.C level. Almost 79% had sanitary latrine. . It was found that 28% peoples were and poor their monthly income was 3,000-6,000 taka, 40% peoples were middle class their monthly income was 6,000-9,000 taka, about 24% peoples were rich their monthly income was 9,000-12,000 and lest 8% peoples income were 12,000+. 90% tube wells were arsenic free and only 10% tube wells are arsenic contaminated. About 77% were related with the BWDB and rests 13% were not the beneficiary of the BWDB. About 86% respondants were benifited by the activities of the BWDB. About 100% of respondents are fully satisfied by the activities of BWDB in arsenic test. It was shown that the social life of the respondents of Bhadrabila Union Parisad was getting better. The most important thing is almost 100% of the respondents were satisfied by the activities of BWDB. Asian J. Med. Biol. Res. June 2016, 2(2): 297-303

An Intelligent Monitoring System of Vehicles on Highway Traffic

Abstract: Vehicle speed monitoring and management of highways is the critical problem of the road in this modern age of growing technology and population. A poor management results in frequent traffic jam, traffic rules violation and fatal road accidents. Using traditional techniques of RADAR, LIDAR and LASAR to address this problem is time-consuming, expensive and tedious. This paper presents an efficient framework to produce a simple, cost efficient and intelligent system for vehicle speed monitoring. The proposed method uses an HD (High Definition) camera mounted on the road side either on a pole or on a traffic signal for recording video frames. On the basis of these frames, a vehicle can be tracked by using radius growing method, and its speed can be calculated by calculating vehicle mask and its displacement in consecutive frames. The method uses pattern recognition, digital image processing and mathematical techniques for vehicle detection, tracking and speed calculation. The validity of the proposed model is proved by testing it on different highways.

Evaluation of the prognostic significance of CDK6 in breast cancer

Abstract: Cyclin-dependent kinase (CDK) gene family is an important cell cycle progression regulator, which may function as a tumor suppressor. We performed a systematic onco-informatics analysis to investigate the prognostic value of CDK6 in breast cancer. CDK6 expression was evaluated using the Oncomine and UALCAN database. The relevance between CDK6 level and clinical parameters and survival data in breast cancer was analyzed using the bc-GenExMiner, and Kaplan–meier plotter databases. The methylation status and heat map of CDK6 were analyzed by utilizing the UCSC Xena and UALCAN. It was identified that CDK6 was under-expressed in different subtypes of breast cancer. Estrogen receptor (ER) and progesterone receptor (PR) were negatively correlated with CDK6 expression. On the other hand, nottingham prognostic index (NPI), human epidermal growth factor receptor-2 (HER-2) status, basal-like status, scarff–bloom–richardson (SBR) grade, and triple-negative status were positively correlated with CDK6 level in breast cancer samples with respect to normal tissues. Besides, a positive correlation between CDK6 and pronecroptosis E3 ubiquitin ligase (PELI1) gene expression was confirmed. Our study revealed that CDK6 might be used as a biomarker for breast cancer prognosis with PELI1. However, more comprehensive experimental data are needed to clarify the value of CDK6 in breast cancer.